American literature -- Periodicals; Literature -- Periodicals
_Alcohol and Acute Infections_
In connection with experiments in rendering animals and men immune
from certain contagious diseases through inoculation with specific
serums, Deléarde, working in Calmette's laboratory in Lille, showed
that alcoholized rabbits are not protected by inoculation, as normal
ones are, against hydrophobia. Moreover, he reports the case of
an intemperate man, bitten by a mad dog, who died notwithstanding
anti-rabic treatment, whereas a boy of thirteen, much more severely
bitten by the same dog on the same day, recovered under treatment.
Deléarde strongly advises any one bitten by a mad dog to abstain from
alcohol, not only during the anti-rabic treatment but for some months
thereafter, lest the alcohol counteract the effects of the protective
serum.
Similar laboratory experiments have been made by Laitenan, who became
fully convinced that alcohol increases the susceptibility of animals to
splenic fever, tuberculosis, and diphtheria. Dr. A. C. Abbott, of the
University of Pennsylvania, made an elaborate series of experiments to
test the susceptibility of rabbits to various micro-organisms causing
pus-formation and blood poisoning. He found that the normal resistance
of rabbits to infection from this source was in most cases "markedly
diminished through the influence of alcohol when given daily to a stage
of acute intoxication." "It is interesting to note," Dr. Abbott adds,
"that the results of inoculation of the alcoholized rabbits with the
erysipelas coccus correspond in a way with clinical observations on
human beings addicted to the excessive use of alcohol when infected by
this organism."
Additional confirmation of the deleterious effects of alcohol in this
connection was furnished by the cats and dogs of Professor Hodge's
experiments, already referred to. All of these showed peculiar
susceptibility to infectious diseases, not only being attacked earlier
than their normal companions, but also suffering more severely, This
accords with numerous observations on the human subject; for example,
with the claim made some years ago by McCleod and Milles that Europeans
in Shanghai who used alcohol showed increased susceptibility to Asiatic
cholera, and suffered from a more virulent type of the disease.
Professor Woodhead points out that many of the foremost authorities now
concede the justice of this view, and unreservedly condemn the giving
of alcohol, even in medicinal doses, to patients suffering from cholera
or from various other acute diseases and intoxications, including
diphtheria, tetanus, snake-bite, and pneumonia, as being not merely
useless but positively harmful. Even when the patient has advanced far
toward recovery from an acute infectious disease, it is held still
to be highly unwise to administer alcohol, since this may interfere
with the beneficent action of the anti-toxins that have developed in
the tissues of the body, and in virtue of which the disease has been
overcome.
_The Ally of Tuberculosis_
Public-domain text, read in full here on John Shaqi.
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