Under these influences transmitted to, or at least shared by, the medical profession, the old question between “Nature,” so called, and “Art,” or professional tradition, has reappeared with new interest. I say the old question, for Hippocrates stated the case on the side of “Nature” more than two thousand years ago. Miss Florence Nightingale,--and if I name her next to the august Father of the Healing Art, its noblest daughter well deserves that place of honor,--Miss Florence Nightingale begins her late volume with a paraphrase of his statement. But from a very early time to this there has always been a strong party against “Nature.” Themison called the practice of Hippocrates “a meditation upon death.” Dr. Rush says: “It is impossible to calculate the mischief which Hippocrates has done, by first marking Nature with his name and afterwards letting her loose upon sick people. Millions have perished by her hands in all ages and countries.” Sir John Forbes, whose defence of “Nature” in disease you all know, and to the testimonial in whose honor four of your Presidents have contributed, has been recently greeted, on retiring from the profession, with a wish that his retirement had been twenty years sooner, and the opinion that no man had done so much to destroy the confidence of the public in the medical profession. In this Society we have had the Hippocratic and the Themisonic side fairly represented. The treatise of one of your early Presidents on the Mercurial Treatment is familiar to my older listeners. Others who have held the same office have been noted for the boldness of their practice, and even for partiality to the use of complex medication.