All ages and both sexes were affected by this fever. Seven of the practitioners of physic were confined by it nearly at the same time. The city, during the prevalence of the fever, was filled with an unusual number of strangers, many of whom, particularly the Friends (whose yearly meeting was held in the month of September), were affected by it. No other febrile disease was observed during this time in the city. This fever generally came on with rigour, but seldom with a regular chilly fit, and often without any sensation of cold. In some persons it was introduced by a slight sore throat, and in others by a hoarseness which was mistaken for a common cold. A giddiness in the head was the forerunner of the disease in some people. This giddiness attacked so suddenly, as to produce, in several instances, a faintness, and even symptoms of apoplexy. It was remarkable, that all those persons who were affected in this violent manner, recovered in two or three days. I met with one instance of this fever attacking with coma, and another with convulsions, and with many instances, in which it was introduced by a delirium. The pains which accompanied this fever were exquisitely severe in the head, back, and limbs. The pains in the head were sometimes in the back parts of it, and at other times they occupied only the eyeballs. In some people, the pains were so acute in their backs and hips, that they could not lie in bed. In others, the pains affected the neck and arms, so as to produce in one instance a difficulty of moving the fingers of the right hand. They all complained more or less of a soreness in the seats of these pains, particularly when they occupied the head and eyeballs. A few complained of their flesh being sore to the touch, in every part of the body. From these circumstances, the disease was sometimes believed to be a rheumatism; but its more general name among all classes of people was, the _break-bone fever_. I met with one case of pain in the back, and another of an acute ear-ach, both of which returned periodically every night, and without any fever. A nausea universally, and in some instances a vomiting, accompanied by a disagreeable taste in the mouth, attended this fever. The bowels were, in most cases, regular, except where the disease fell with its whole force upon them, producing a dysentery. The tongue was generally moist, and tinctured of a yellow colour. The urine was high coloured, and in its usual quantity in fevers. The skin was generally moist, especially where the disease terminated on the third or fourth day. The pulse was quick and full, but never hard, in a single patient that came under my care, till the 28th of September. It was remarkable, that little, and, in some instances, no thirst attended this fever. A screatus, or constant hawking and spitting, attended in many cases through the whole disease, and was a favourable symptom.