3. _Alternation of dropsies with certain diseases which were evidently accompanied by excess of action in the arterial system._ I have seen anasarca alternate with vertigo, and both ascites and anasarca alternate with tonic madness. A case of nearly the same kind is related by Dr. Mead. Dr. Grimes, of Georgia, informed me that he had seen a tertian fever, in which the intermissions were attended with dropsical swellings all over the body, which suddenly disappeared in every accession of a paroxysm of the fever. 4. _The occasional connection of certain dropsies with diseases evidently of an inflammatory nature_, particularly pneumony, rheumatism, and gout. 5. Spontaneous _hæmorrhages_ from the lungs, hæmorrhodial vessels, and nose, cases of which shall be mentioned hereafter, when we come to treat of the cure of dropsies. 6. _The appearance of dropsies in the winter and spring, in habits previously affected by the intermitting fever._ The debility produced by this state of fever, frequently disposes to inflammatory diathesis, as soon as the body is exposed to the alternate action of heat and cold, nor is this inflammatory diathesis always laid aside, by the transition of the intermitting fever into a dropsy, in the succeeding cold weather. 7. _The injurious effects of stimulating medicines in certain dropsies_, prove that there exists in them, at times, too much action in the blood-vessels. Dr. Tissot, in a letter to Dr. Haller, "De Variolis, apoplexia, et hydrope," condemns, in strong terms, the use of opium in the dropsy. Now the bad effects of this medicine in dropsies, must have arisen from its having been given in cases of too much action in the arterial system; for opium, we know, increases, by its stimulating qualities, the action and tone of the blood-vessels, and hence we find, it has been prescribed with success in dropsies of too little action in the system. 8. _The termination of certain fevers in dropsies in which blood-letting was not used._ This has been ascertained by many observations. Dr. Wilkes relates[36], that after "an epidemical fever, which began in Kidderminster, in 1728, and soon afterwards spread, not only over Great Britain, but all Europe, more people died dropsical in three years, than did perhaps in twenty or thirty years before," probably from the neglect of bleeding in the fever. [36] Historical Essay on the Dropsy, p. 326.