When Columbus returned to Europe a second time he left behind him, under orders of his brother, a hundred of his companions in arms, who were a collection of adventurers from all the nations of the earth. These men committed all sorts of excesses among the unfortunate Indians—steeping themselves in lust and every manner of crime, violating the women, and indulging in wholesale debauchery. Says Charles Renaut: “Looking at matters from this standpoint, I am ready to believe that the Spaniards carried the disease to the natives of Hispanola, and that the latter did not give the malady to the Spanish.” We shall not dwell further on the origin of syphilis, nor its connection with leprosy and other cutaneous maladies which were so prevalent in Europe throughout the Middle Ages. We may consider the disease as something new, and trace its period of invasion and development to the discovery of America, or assert that it arose from a semi extinct affection (leprosy), assuming a new type under the influence of a special epidemic constitution. One thing is clearly proven, _i.e._, that syphilis was preceded by contagious venereal affections, which lost the irregular and malignant forms of the fifteenth century. When then the civilized nations of earth create a true Public Health Service, syphilis will be vanquished, and will pass away to the ranks of other extinct maladies. THE DEMONOMANIA OF THE MIDDLE AGES. ORIGIN OF MAGIC AND SORCERY From the day that Louis XIV. dissolved the Parliament of Rouen, which had condemned several persons in the Province of Vire to death for the crime of sorcery, but few sorcerers have been seen in France. It was in 1682 that Urbain Grandier was tortured and burned alive for having launched a malediction against the Ursulines of Loudun. A violent reaction occurred against the Inquisitors, theologians, and their accomplice butchers, thanks to the courageous intervention of eminent philosophers and savants, who were justly indignant at the crimes of the Roman Catholic priesthood. This reaction clearly demonstrated the fact that the innumerable victims of religious intolerance in the Middle Ages were not sorcerers, nor possessed of the devil, nor minions of Hell. Psychologists and moralists claimed that the victims of these delusions were insane, persons suffering from semi delusions, subjects of monomania. Science classed these unfortunates into several groups, among which may be enumerated persons afflicted with hallucinations, demonomaniacs, erotomaniacs, subjects of lycanthropy, etc., without counting vampires, choreomaniacs, lypemaniacs, and others whose attacks are recognized by medical science.