After rapid progress in classical and dialectic studies, he went to the university of Bologna, and in his twentieth year maintained various public disputations before a general chapter of his order at Genoa, with erudition and success which astonished his audience, and gained him the marked commendation of his superiors. He then graduated in philosophy and theology at Pavia, and in his public displays distinguished himself by a simple and perspicuous style of argument comparatively exempt from the jingle of words that usually characterised these exercises. His celebrity extending in all directions, he was engaged by the authorities of many large towns to deliver lectures, which were attended by the most learned ecclesiastics, his preaching being not less acceptable to the people of all ranks. His friendship and counsel were sought by the distinguished men of his time, including Cardinal Bessarion; and he employed his pen in various religious controversies, especially in one, carried by other disputants to blows, between two branches of Franciscans, the Minims and Predicant Friars, as to "whether the blood of Christ shed in his passion partook of his divinity." Having attained the rank of General, he proved most zealous in the inspection and reform of the convents under his jurisdiction, personally visiting them in all quarters. At length, in 1467, he was made Cardinal by Paul II., whom he was chosen to succeed on the 9th of August, 1471. We have had occasion, in a previous portion of this work, to notice the policy of Sixtus as it affected the duchy of Urbino, and it forms no part of our plan to enter further into the events of his pontificate. Neither need we detail those in that of his nephew Julius II., except in so far as they fall to be narrated in our Third and Sixth Books. Our present purpose is to offer a condensed view of the della Rovere family, preceding its establishment in the sovereignty of Urbino, and to enliven what would otherwise be a dry genealogical sketch, by a few passing observations on the character of its two Pontiffs, and on the influence of their reigns. The children of Ludovico Leonardo della Rovere by Luchina Stella Muglione were these:-- 1. FRANCESCO, afterwards Sixtus IV. 2. RAFFAELE, whose line will presently occupy our attention. 3. A sister, whose husband Giovanni Basso and children were adopted into the family of della Rovere and bore that name. They were:-- 1. GIROLAMO of Recanate, made Cardinal of S. Chrisogono in 1477, and died in 1507. 2. ANTONIO, who married in 1479 Caterina Marciana, niece of Ferdinand of Naples, and died soon after. 3. GUGLIELMO, who died in 1482. 4. FRANCESCO, Prior of Pisa. 5. BARTOLOMEO.[208] 4. IOLANDA, who married Girolamo Riario, and, dying in 1471, left:-- 1. CARDINAL PIETRO RIARIO, the favourite of his Uncle Sixtus IV., who died in 1474.