Siena, originally Ghibelline, had, during the recurring convulsions of a nominally democratic government, remained in some measure devoted to the imperialist party. But, irritated by the licence of their Spanish garrison, and alarmed at a rumoured intention of Charles V. to seize their state, and exchange it with the Farnesi for that of Parma, the citizens, in 1552, foolishly listened to the intrigues of French emissaries, and, with the Count of Pitigliano's aid, ousted their oppressors. In the campaign which followed, Siena was under French protection, whilst Florence efficiently co-operated with the imperialists against her, the Pope maintaining an armed neutrality. The duties of Guidobaldo were thus limited to an occupation of Bologna, in order to protect the ecclesiastical territories and his own state, on the passage of French troops into Tuscany. That his wishes favoured the independence of Siena appears from his having, at the election of Marcellus II., in April, 1554, recommended an intervention in its favour; but it was too late, as the city had already capitulated, and was soon after finally annexed to Florence. The successor of Julius III., who died in March, 1555, was Marcello Cervini, Bishop of Gubbio; and the Duke of Urbino congratulated himself on seeing a personal friend mount the throne of St. Peter. But his satisfaction was transient. Popular superstition awarded an early death to any Pontiff who should take for title his Christian name: the fate of Adrian VI. had verified the omen; and, after a reign of but three weeks, Marcellus was carried to the tomb. Guidobaldo immediately took armed possession of the Roman gates for protection of the conclave; but the election of Cardinal Caraffa as Paul IV. passed off satisfactorily, and his energy was rewarded by a confirmation in his command, and the restoration of the Prefecture of Rome, with reversion to his son, an honour which, though long held by his father and grandfather, had been enjoyed for the last seventeen years by the Farnesi. CHAPTER XLIII The Duke's domestic affairs--Policy of Paul IV.--The Duke enters the Spanish service--Rebellion at Urbino severely repressed--His death and character--His children.