and suprarenal; two, gonads, thyroid, pituitary and thymus." Further investigation only can accurately determine the exact relation which exists between disturbance of these glands and the presence of mental deficiency. Attention was called some time since to the fact that the injection of adrenalin leads to an increase in blood pressure. This has been discussed by Falta, Newburgh, Nobel and others. Neubürger[112] made a study of thirty-nine cases, seven of which were normal, the others including alcoholism, neurasthenia, manic-depressive, etc., but not dementia praecox. A fairly well marked rise of blood pressure followed adrenalin injection very quickly, reaching its maximum in from six to twelve minutes. He found the reaction diminished or absent in eighty per cent of the sixty-three cases of dementia praecox which he examined, but does not advance the claim that this can be utilized for diagnostic purposes. Walter and Krumbach[113] found an increased pressure in sixty per cent of normal control cases and obtained similar reactions in dementia praecox. Schmidt, on the other hand, confirmed the findings of Neubürger. Emerson[114] found status lymphaticus in over twenty-nine per cent of his cases of dementia praecox and Davis[115] found the same condition in twenty-four per cent of war neuroses in a series of over one hundred cases. These findings, however, lack confirmation by other observers. Straus[116] includes as mental symptoms in thyroidal disbalance: sluggish mental reactions alternating with sparkling wit, irritability, general moodiness and depression, difficulty in thought with inability to concentrate, forgetfulness, fatigability and somnolence. Turro[117] has shown that all of the physical evidences of fright—pallor, dilatation of the pupils, rapid pulse, cutis anserinus, perspiration, etc., can be produced experimentally by the injection of epinephrin in certain cases. Knauer and Billigheimer[118] have called attention to the striking similarity between the functional changes to be found in disturbances of the vegetative (sympathetic) nervous system and certain manifestations associated with fear neuroses. They attribute these disturbances to congenital inferiority, toxic sources, emotional shock or fatigue.