That is the whole evidence as to the incident, and as all the bottles in the house were analyzed, and none found to contain _even a trace of arsenic_ except the Clay and Abraham’s bottle--which James Maybrick was not taking at that time--the judge could not properly direct the jury to regard it as a matter of suspicion; _but he did do so_. He referred to this incident thus: “On the 28th April (the day after the Wirrall Races) Mrs. Maybrick sent for Dr. Humphreys, and afterward she was seen pouring medicine from one bottle into another.” It is submitted that this was _a serious misdirection_. The other occasion was on Friday, the 10th of May, when Michael Maybrick, seeing Mrs. Maybrick changing a medicine from one bottle to another in the bedroom, took the bottles away and had the prescription made up again, saying: “Florrie, how dare you tamper with the medicine?” Mrs. Maybrick explained that she was only putting the medicine into a larger bottle because there was so much sediment. Nurse Callery was present and there was no concealment about what she was doing, and the bullying conduct of Michael was absolutely without any sort of justification. _These bottles were analyzed and found to be harmless._ Mr. Justice Stephen turned this incident, which occurred on the afternoon before death, and after she had been prevented from attending on her husband, against Mrs. Maybrick, thus--quoting Michael’s evidence: “In the bedroom I found Mrs. Maybrick pouring from one bottle into another and changing the labels, and I said, ‘Florrie, how dare you tamper with the medicine?’” And Justice Stephen continued: “Verily, this was a strange--I don’t say strange considering the circumstances--but dreadfully unwelcome remark to make to a lady in her own house, when she was in attendance on her husband, and something which showed the state of feeling in his mind, and must have attracted her attention.” It is submitted that this was a _misdirection_. MISDIRECTION AS TO ADMINISTRATION WITH INTENT TO KILL