In a skirmish near Bryson City (then Charleston), Swain county, North Carolina, about a year after enlistment, a small party of Cherokee--perhaps a dozen in number--was captured by a detachment of Union troops and carried to Knoxville, where, having become dissatisfied with their experience in the Confederate service, they were easily persuaded to go over to the Union side. Through the influence of their principal man, Digane'ski, several others were induced to desert to the Union army, making about thirty in all. As a part of the Third North Carolina Mounted Volunteer Infantry, they served with the Union forces in the same region until the close of the war, when they returned to their homes to find their tribesmen so bitterly incensed against them that for some time their lives were in danger. Eight of these are still alive in 1900. [436] One of these Union Cherokee had brought back with him the smallpox from an infected camp near Knoxville. Shortly after his return he became sick and soon died. As the characteristic pustules had not appeared, the disease seeming to work inwardly, the nature of his sickness was not at first suspected--smallpox having been an unknown disease among the Cherokee for nearly a century--and his funeral was largely attended. A week later a number of those who had been present became sick, and the disease was recognized by Colonel Thomas as smallpox in all its virulence. It spread throughout the tribe, this being in the early spring of 1866, and in spite of all the efforts of Thomas, who brought a doctor from Tennessee to wait upon them, more than one hundred of the small community died in consequence. The fatal result was largely due to the ignorance of the Indians, who, finding their own remedies of no avail, used the heroic aboriginal treatment of the plunge bath in the river and the cold-water douche, which resulted in death in almost every case. Thus did the war bring its harvest of death, misery, and civil feud to the East Cherokee. [437] Shortly after this event Colonel Thomas was compelled by physical and mental infirmity to retire from further active participation in the affairs of the East Cherokee, after more than half a century spent in intimate connection with them, during the greater portion of which time he had been their most trusted friend and adviser. Their affairs at once became the prey of confusion and factional strife, which continued until the United States stepped in as arbiter.