Martin Fernandez de Enciso, a wealthy lawyer (_bachiller_) of Santo Domingo, had been appointed by Ojeda _alcalde mayor_ of Nueva Andaluçia, and had been left behind to follow his chief with stores and recruits. On his way to San Sebastian he stopped at Cartagena; found no difficulty in making friends with the natives who had opposed Ojeda so stoutly; and while awaiting there the completion of some repairs on a boat, was surprised by the appearance of a brigantine containing the remnant of the San Sebastian colony. When Ojeda had sailed with Talavera he had left Pizarro, the future conqueror of Peru, in command, with orders to hold the place for fifty days, and then, if succor had not arrived, to make the best of his way to Santo Domingo. Pizarro had waited more than fifty days, until the colonists had dwindled to a number not too large for the two little vessels at his disposal. In these they had then left the place. But soon after clearing the harbor one of his brigantines, struck by a fish, had gone down with all on board; and it had been with much difficulty that the other had been navigated to Cartagena. Enciso, commander now that Ojeda and La Cosa were gone, determined to return to San Sebastian; but, while rounding the Punta Caribana, the large vessel laden with the stores went on the rocks and became a total loss, the crew barely escaping with their lives. They were now in as bad a plight as before; and decided, at the suggestion of Vasco Nuñez de Balbóa, to cross the Gulf of Urabá to a country where the natives did not use poisoned arrows, and where, therefore, foraging would not be so dangerous as at San Sebastian.[622] The removal to the other side of the gulf was safely carried out, and the natives driven from their village. The Spaniards settled themselves here, and called the place Santa Maria del Antigua del Darien. Provisions and gold were found in abundance; but Enciso, declaring it unlawful for private persons to trade with the natives for gold, was deposed; for, as Vasco Nuñez said, the new settlement was within the jurisdiction of Nicuesa, and therefore no obedience whatever was due to Enciso. A municipal form of government was then instituted, with Vasco Nuñez and Zamudio as _alcaldes_, and Valdivia as _regidor_. But the Antigua settlers were no more disposed to obey their chosen magistrates than they had been to give obedience to him who had been appointed to rule over them, and they soon became divided into factions. At this juncture arrived Rodrigo Enriquez de Colmenares, whom Nicuesa had left at Española to follow him with recruits and provisions. Colmenares easily persuaded the settlers at Antigua to put themselves under the government of Nicuesa; and then, accompanied by two agents from Darien, sailed away in search of his chief. Nicuesa, after aiding Ojeda at Cartagena, had sailed for Castilla del Oro; but while coasting its shores had become separated from the rest of his fleet, and had been