Neurosyphilis : $b Modern systematic diagnosis and treatment presented in one hundred and thirty-seven case historiesSouthard, Elmer Ernest
Science
Neurosyphilis : $b Modern systematic diagnosis and treatment presented in one hundred and thirty-seven case histories
Southard, Elmer Ernest
Neurosyphilis
“It consists in the proper use of salvarsan and mercury begun at
the earliest possible moment after infection and kept up till all
biochemical evidence of the disease has ceased, while the
metabolism of the individual is maintained as nearly normal as
possible. But the physician does not do his whole duty when he has
accomplished this. He must solicitously watch the individual to
see that no evidence reappears for months and even years after the
apparent cure. As an index of such reappearance the Wassermann
test of the blood serum and of the cerebrospinal fluid is the
safest guide.
“Until there is a definite unanimity of belief among physicians as
to when the treatment of syphilis shall be begun, and some concert
of action as to what constitutes the adequate treatment of
syphilis, we cannot hope to make any considerable progress in the
prevention of syphilis of the nervous system, save by educating
the individual toward infection.”
=TABETIC NEUROSYPHILIS may produce symptoms chiefly if not entirely
in the region supplied by the CERVICAL plexus (“cervical tabes”).=
=Case 31.= Paul Halleck, 35, was a salesman who had begun to find it
hard to carry his sample case, since he was unable to tell whether or
not he had it in his hand. There was not only an anesthesia of the
hands, but they felt numb and there was often a tingling sensation. Of
late it had become hard for Halleck to dress himself or to write, and
these symptoms had been slowly growing worse. There was no other
complaint. There was, however, a history of a chancre about 7½ years
before, which had been followed by a rash and a sore throat. There had
been treatment with mercury and potassium iodid alternating for a period
of two years.
=Physically=, there was no evidence of disease except =neurologically=.
The pupils were unequal (the right larger than the left) and reacted
slowly to accommodation and not at all to light. A marked ataxia of the
hands was shown in coat-buttoning. The finger-to-nose test showed a
marked dysmetria. Arm-jerks as well as knee- and ankle-jerks were
absent. There was a slight swaying in the Romberg position but no true
Romberg sign. There was no difficulty in locomotion. Both blood and
spinal fluid proved positive to the W. R.; globulin and albumin were
increased. The gold sol reaction was syphilitic, and there were 85 cells
per cmm.
This case is probably not a pure example of CERVICAL TABES, since the
knee-jerks are also absent, and we may suppose a degree of lumbar spinal
cord changes in addition to the cervical changes. It well illustrates,
however, that the tabetic involvement of the cord may be quite
generalized and that it may strike high as well as low.
=ERB’S SYPHILITIC SPASTIC PARAPLEGIA.=
Public-domain text, read in full here on John Shaqi.
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