It is possible that the hemorrhage had taken place some time before the patient’s fall and that the brain substance had swollen in consequence. Just before the fall she had a weeping spell. The =anatomical diagnoses= were as follows: Obesity, unequal pupils, fresh wound near left ear, edema of legs, slight focal adhesive pleuritis, hypostatic congestion of lungs, chronic endocarditis, chronic myocarditis, congestion of kidneys, congestion of pancreas, subacute splenitis, chronic adhesive pelvic peritonitis, hematoma and cystic condition of Fallopian tubes, =calvarium dense= and thick, subdural hemorrhage, slight =chronic leptomeningitis=, general =cerebral atrophy=, marked in tips of =frontal lobes=, old =cyst of softening= between left corpora albicantia and optic chiasm, small punctures of left ear drum, drums opaque, =chronic spinal leptomeningitis=; brain weight, 1190 grams. There were marked firm interadhesions between dura and pia throughout. A lumbar puncture soon after admission in 1907 had shown: Per cent Endothelial cells 10 Lymphocytes 30 Plasma cells 0 Phagocytes 0 Polymorphonuclear cells 51 Unclassified 9 Fibroblasts 0 Cells in 100 fields 125 It will be noted that the lumbar puncture yielded no plasma cells and yet showed 30% of lymphocytes. Alzheimer, in 1904, attempted to distinguish the histology of the cerebral syphilitic from that of the general paretic, maintaining that _lymphocytosis was the characteristic feature of the ordinary neurosyphilitic_, _whereas plasma cells were associated with the lymphocytes in the paretic_. This case showed =lymphocytic= deposits. To be sure, they were decidedly subordinate in the cerebral cortex, cerebellum, and basal ganglia, to the marked evidences of nerve cell destruction, although there were perivascular infiltrations about a few of the larger vessels in the white matter of the cerebral cortex. The spinal cord, however, showed a most severe infiltration, especially in the gray matter, where the infiltration accompanied severe nerve cell changes and arterial changes. The pia mater of the spinal cord was also packed with mononuclear elements, among which, however, no plasma cells could be found.