The patient, however, has not been entirely well, for in place of the generalized convulsions, he has had minor seizures, beginning as a rule with a tingling sensation in the right hand, extending up the arm, down the trunk and leg, and through the right side of the face, with a bitter sensation on the right half of the tongue. The patient maintains that this sensation is absolutely confined to the right half of the body (in this connection we may recall case Morton (1), in which there was also a hemiplegia together with other apparently hysterical symptoms at several times during the long course of a disease with abundant structural correlations). During these minor seizures, the patient is unable to talk, although he does not lose consciousness and is entirely aware of everything going on about him. These attacks have of late been growing somewhat less frequent. =LOSS OF DEEP REFLEXES= NEUROSYPHILIS NEURITIS (alcohol, diabetes, diphtheria, lead, arsenic, tubercle, cachexia, etc.) Peripheral nerves sensory or motor PERIPHERAL NERVE PALSIES TEMPORARILY FROM COMPRESSION BY TOURNIQUET FRIEDREICH’S ATAXIA SUBACUTE COMBINED DEGENERATION OF POSTERIOR AND LATERAL COLUMNS Posterior column disease FOCAL LESION IN GRAY MATTER OF CORD INFANTILE PARALYSIS (ACUTE ANTERIOR POLIOMYELITIS) PROGRESSIVE MUSCULAR ATROPHY (chronic anterior poliomyelitis) Anterior cornua of cord AMYOTROPHIC LATERAL SCLEROSIS SYRINGOMYELIA THROMBOSIS OF ANTERIOR SPINAL ARTERY LANDRY’S PARALYSIS Anterior cornua and peripheral motor nerves MYOPATHIES (pseudohypertrophic and atrophic types) MuscLe itself AMYOTONIA CONGENITA FAMILY PERIODIC PARALYSIS (during attacks) INCREASED INTRACRANIAL PRESSURE (especially hydrocephalus and tumors of posterior fossa) PNEUMONIA IMMEDIATELY AFTER ATTACK OF MAJOR EPILEPSY (post-epileptic coma) TOXIC COMA (uremia, morphine, etc.) DURING SPINAL ANESTHESIA COMPLETE TRANSVERSE LESION OF CORD PURVES STUART CHART 16 1. What is the cause of the negative serum W. R.? It is claimed that 3 to 5% of all cases of general paresis yield a negative blood serum. In this particular case, there had been considerable treatment, including some Swift-Ellis treatment, so that it may be that this treatment had reduced a formerly positive blood serum W. R. to a negative one.