With such an anti-hysterical reputation as the empirical use had given to _Pothos foet._, it might fairly be anticipated that its pathogenesis would be distinguished by a paucity of objective _data_, for only a tyro in pharmacodynamics, or a "Regular," would expect to find a full-lined picture of hysteria in any "proving." And so we have in the "abstract" a flux of subjective symptoms, "erratic" enough for hysterical elements, and still further characterized by an apparent evanescence, as if its phenomena of sensory disturbance were as fleeting and unsubstantial as those of an hysterical storm. The _will-o'-the-wisp-like_ character of its subjective symptoms, and its physometric property (hinted at in the pathogenesis and emphasized in Thacher's case) are the features that will chiefly impress one in studying this distinctively American remedy. That the "abstract of symptomes" evinces a cautious trial of this drug, and that more heroic experiments will add to our knowledge of its pathogenetic properties, are plain deductions from the absence in the "abstract" of such pronounced effects as Bigelow observed and also from the evidence of the _usus in morbis_. The remedy needs an efficient proving, especially in the female organism. AN APPLICATION OF POTHOS FOETIDA. Miss B----, æt. 20; a tall, spare brunette, and a good specimen of Fothergill's _Arab type_, brainy and vivacious. General health has been good, but she was never robust; could not go to school regularly. Between her thirteenth and fifteenth years grew rapidly in stature, and then she was easily wearied on walking; knees tired and limbs ached. Had good digestion through the growing period, but subsequently became subject to "bloat of wind" in abdomen. These meteoristic attacks came when lying down. A "weight rises from the abdomen up to the heart." She must at once spring up. This condition is relieved by eructating, by liquor, and by drinking hot water. The night attacks of meteorism are by far the worst. _She is now subject to them._ [Her grand-mother had such "spells of bloating;" would spring out of bed at night, lose consciousness, and "bloat up suddenly." If she had such an attack when dressed, they had often been obliged to cut open her clothes.] Patient has found that apples, tomatoes, cabbage and onions disagree with her; no other food. She is constipated--"wants to and can't." Her hair is unusually dry; scalp full of dandruff; skin, generally, soft and flexible. She has frequent epistaxis; has had four and five attacks a day. Blood bright red, "runs a perfect stream," does not clot at the nostrils. Has previously a "heavy feeling" in the head, which the bleeding relieves. In appearance she is "the picture of health;" good complexion, fairly ruddy cheeks, sparkling eyes--in a word, she is an incarnated protest against "single blessedness."