Besides all these, I think individual idiosyncrasy has a great deal to do. The season of the year has some influence. It is usually observed in this country that those who are subject to periodical attacks of asthmatic fits are more prone to an attack either during the full or the new moon, or at both the times. I believe if it is properly watched this fact will be evident all over the world. Same is true of some other diseases, as chronic cough, chronic fevers, rheumatism, either acute or chronic, gout, elephantiasis, other glandular enlargements, etc., get aggravated or are prone to aggravation during such changes of the moon. Then some people get more severe and frequent fits during the winter than the summer and the others more during the summer than the winter. Let me here tell you that the Indian summer is very different from either the English or the American. Some part of the Indian summer season is quite rainy and the atmosphere is saturated with moisture and other irritating ingredients, consequently a class of asthmatic people suffer more during this season. I noticed to this class of cases _Blatta orientalis_ will prove most efficacious. I have used it in bronchial and nervous asthma with better success than the stomachæ. SECOND PAPER. I have of late tried _Blatta orientalis_ indiscriminately in almost all cases of asthma that have come under my treatment, and I am glad to say I have received good results in most cases, as the reports of some of the clinical cases will show. I have not come to any definite use of this drug yet, but I shall only mention a few facts that I have observed during its use. It acts better in low potency and repeated doses during an attack of asthma; when the spasm subsides, the terminal asthmatic cough with wheezing and slight dyspnoea, etc., is better relieved with higher potencies; the low potency, if continued after the spasmodic period is over, will make the cough more troublesome and harassing to the patient and the expectoration tenacious, thick and very difficult to raise, but this will not be the case if the potency is changed. I had this difficulty in a few cases when I was less acquainted with the action of the drug, but now I manage my cases better. In four patients who continued the drug for some time in the low potency, during the paroxysm and after it was over, the cough became dry and hacking with little or no expectoration, the streaks of blood appeared in the sputa, which the patients had never observed in the course of their long illness. This appearance of blood in their sputa was the cause of a great anxiety to them and made them hurry over to my office. On inquiry I learned from two of them--one a lady and the other a young man--that while taking this remedy they felt a sensation all over the body, for four or five days previous to the appearance of the blood, as if heat were radiating from the ears, eyes, nose, top of the head, palms of the hands and soles of the feet.