In 1850 cholera broke out in Jamaica, and raged for a greater portion of the year, and a doctor who was living at Mary Seacole's house gave her many valuable hints concerning the treatment of cholera cases. Before long the knowledge thus obtained proved to be the means of saving many lives. Shortly after the cholera had ceased to rage in Jamaica Mary Seacole proceeded on a visit to her brother, who owned a large, prosperous store at Cruces in California. On arriving there, she found the place crowded with a mixed mob of gold-diggers and speculators, some proceeding to the gold-fields, others returning. The men returning were drinking, gambling and "treating" those who were bound for the gold-fields. It was a degrading sight, and Mary Seacole wished that she had not left Jamaica. There was nowhere for her to sleep, wash or change her travel-stained clothes, for every room in her brother's house was engaged by the homeward-bound gold-diggers. Until they departed she had to manage to exist without a bed. These parties of miners arrived at Cruces weekly, and the scenes of dissipation were the same on each occasion. Quarrels which ended in the death of one of the combatants were frequent and little noticed, but the very sudden death of a Spaniard who resided at Cruces caused great excitement. He had dined with Mary Seacole's brother, and on returning home was taken ill and suddenly died. Suspicion fell upon Mary Seacole's brother, and it was said openly that he had poisoned the man. Mary Seacole, indignant at the accusation brought against her brother, went to see the body, and knew at once that the man had died from cholera. No one believed her, but the following morning a friend of the dead man was taken ill with the same disorder, and the people who had scoffed at her became terror-stricken. There was no doctor at Cruces, and Mary Seacole set herself to battle single-handed with the plague. Fortunately, she never travelled without her medicine-chest, and taking from it the remedies which had been used in Jamaica with great success she hurried to the sick man's bedside, and by her promptitude was able, under God, to save his life. Two more men were stricken down and successfully treated, and Mary Seacole was beginning to hope that the plague would not spread, when a score of cases broke out in one day. The people were now helpless from terror, and Mary Seacole was the only person who did not lose her presence of mind. Day and night she was attending patients, and for days she never had more than a hour's rest at a time. Whenever a person was stricken, the demand was for 'the yellow woman from Jamaica,' and it was never made in vain.