The Cenozoic era is the age of mammals, so called because during that time brute mammals succeeded reptiles as the rulers of the earth. From the rocks deposited in North America during this era, principally the sediments of fresh-water lakes and the gravel-beds laid down by streams in the Pacific mountain region, a great number of skeletons of truly remarkable mammals, differing widely from anything now living, have been discovered by Joseph Leidy, O. C. Marsh, E. D. Cope, H. F. Osborn, and others. The profound interest attached to this fauna, and the bearings it has on the study of the geographical distribution of animals, climatic changes, etc., is indicated by the fact that it includes forms related to the rhinoceros, elephant, camel, etc., which are not represented among the animals now living on the continent, although having relatives in other and principally tropical countries. During the Psychozoic era mind gained ascendency over brute force, and man became the leader. The mammals continued to dominate the earth throughout the Pleistocene period and were then probably more numerous and of even larger size than during the preceding Tertiary period. During the Pleistocene great climatic changes occurred, and large glaciers existed in several regions which now enjoy a temperate climate and are densely populated. The presence of man in North America during the Pleistocene has not been proved, but important contributions to knowledge concerning the brute mammals, and in reference also to the climatic and physiographic changes, have been made. In stream-deposited gravels, caverns, peat swamps, etc., over the surface of practically the entire continent, the bones of many species of large mammals have been obtained. These include the mastodon and elephant, megatherium, megalonyx, mylodon, a large horse, a great bison, an elk much exceeding the living species in size, a giant beaver, and many others remarkable for their large dimensions as compared with their living representatives. Several of these large animals survived the vicissitudes of climate characteristic of the Glacial epoch, but have since become extinct. The chief contributions to Pleistocene history, however, made by American geologists, are in connection with the records of climatic changes. During the earlier portion of the period, and beginning perhaps in late Tertiary time, the continent in large part at least was more elevated than now and the energetic streams of the mountainous portions eroded deep canyons. To this Sierran epoch, as it is termed, is referred the excavation of the larger valleys of the Sierra Nevada, the world-renowned canyons of the Colorado and Snake Rivers, and probably the deep Valley of the St. Lawrence and the Hudson.