North American Medical and Surgical Journal, Vol. 2, No. 3, July, 1826Various
History
North American Medical and Surgical Journal, Vol. 2, No. 3, July, 1826
Various
Medicine -- Periodicals
In four experiments, Dr. B. removed the left kidney of the rabbit, by
incision on the outer edge. Ligatures were applied to prevent bleeding.
Two died; one in 60 hours, the other in 4-1/2 days: both of
inflammation. One recovered, and lived 5 or 6 weeks, and then died. The
4th also recovered, but died in 5 or 6 weeks. On examination, a sac was
found (in place of the kidney) filled with a semi-fluid substance,
resembling custard, p. 4.
In seven rabbits, removed the spleen. One recovered permanently, and one
lived six months. p. 5.
In five rabbits, opened the abdomen, and punctured the fundus of the
bladder with a lancet. Three of them recovered entirely. p. 6.
In two rabbits, cut off one-fourth of the bladder with scissors, having
applied a ligature first. One died in seven months; the other still
lives in good health.
Into the peritoneum of four rabbits, threw [Symbol: ounce]i of human
urine; then washed it out by injecting tepid water. One died of collapse
in less than 24 hours, and two of inflammation, in 60 and 19 hours
respectively. The fourth is now (12 months) in good health. p. 7.
In seven, injected [Symbol: ounce]xi decoct. quercus into the
peritoneum. Only one recovered.
Dr. B.'s inferences from the foregoing experiments are:
1st. "Large apertures into the peritoneum of the rabbit, do not
immediately induce a dangerous prostration, of strength." p. 9.
2ndly. "Large apertures into the peritoneal sac of the rabbit,
are not necessary, nor perhaps generally, productive of fatal
inflammation."
3dly. "In the rabbit, the kidney, the spleen, and a large piece
of the bladder may be extirpated, without necessarily causing
death; though death under the first operation is probable." p.
10.
4thly. "When the abdomen is laid open, and parts are removed
from it in the rabbit, the first danger arises apparently from
collapse; the second from general inflammation; and the last
from chronic disease." (Vide experiments.)
5thly. "The rabbit's abdomen is very tender, probably no less
so than that of man." See exper.
6thly. "Success in abdominal operations on the rabbit,
furnishes a presumption in favour of success in similar
operations on the human abdomen; and, therefore, from these
experiments, we may infer, _presumptively_, that moderate
openings into the human peritoneum will not necessarily, nor
even generally prove fatal from inflammation or otherwise; and
further, that certain viscera or parts of viscera, not
essential to the welfare of our structure, may be removed from
the belly, without necessarily, or even generally, producing
death. The extirpation of the kidney must be highly dangerous;
but there is a presumption in favour of the successful removal
of the spleen, the ovaries, or even of large pieces of the
bladder." p. 11, 12.
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