North American Medical and Surgical Journal, Vol. 2, No. 3, July, 1826Various
History
North American Medical and Surgical Journal, Vol. 2, No. 3, July, 1826
Various
Medicine -- Periodicals
"Boil, for half an hour, six pounds of coarsely powdered Chinese rhubarb
in six gallons of water, acidulated with two and a half fluid ounces of
sulphuric acid; strain the decoction, and submit the residue to a second
ebullition in a like quantity of acidulated water; strain as before, and
submit it again to a third ebullition. Unite the three decoctions, and
add, by small portions, recently powdered pure lime, constantly stirring
it to facilitate its action on the acid decoction. When the decoction
becomes slightly alkaline, it deposites a red flocculent precipitate,
and the fluid is changed from a yellow to a crimson colour. The
precipitate is then to be separated by passing it through a linen cloth,
and dried; after which, reduce it to powder, and digest in three gallons
of alcohol, at thirty-six degrees, in a water bath, for several hours,
at a moderate heat. Separate this solution from the calcareous
precipitate, and distil off three-fourths of the alcohol. There then
remains a strong solution of rhubarbine, to which add as much sulphuric
acid as will exactly neutralize it. Evaporate this slowly to dryness,
without having access to atmospheric air. The residuum will be of a
brownish-red colour, intermingled with brilliant specks, possessing a
slightly pungent styptic taste, soluble in water, and its odour that of
the native rhubarb." This residuum is the sulphate of rhubarb. (Sulphate
of _rhubarbin._?)
Mr. CARPENTER assures us, that this preparation contains the medicinal
principle of the rhubarb, apart from its inert portion; and considers it
as bearing the same relation to rhubarb, as the sulphate of quinia to
the Peruvian bark. The Chinese rhubarb, at half the price, furnished
twice as much rhubarbin as the reputed Russian, which Mr. C. considers
to be spurious in the Philadelphia market, being the English prepared in
imitation of the Russian.--_Philadelphia Journal of the Medical &
Physical Sciences. May_, 1826.
68. _Alkaline Lozenges of Bicarbonate of Soda._--Mr. D'ARCET proposes
the following formula for these lozenges:--Take of
Bicarbonate of Soda, pure and dry, and in fine powder, 5 parts.
Very white Sugar, in fine powder, 95
Mucilage of Gum Tragacanth, q.s.
Essential oil of Mint, pure and fresh, 2 or 3 drops
for about every 3 ounces of mixture of bicarbonate and sugar.
Shake the bicarbonate and sugar in a well dried bottle, with the view of
mixing them intimately. Withdraw the mixture from the bottle, and add
the mucilage and oil of mint, blending the whole together on a marble.
The mass obtained, is then to be divided into lozenges, which should
weigh, when dried, about 15 grains each. As they slightly attract
moisture, they ought to be kept in a dry place, or in well stopped
bottles.
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