Again, the difference of spirit which is important and of effect in many points (as unconnected spirit, branching spirit, branching and cellular spirit, the first of which is that of all inanimate substances, the second of vegetables, and the third of animals), is placed, as it were, before the eyes by many reducing instances. Again, it is clear that the more refined tissue and conformation of things (though forming the whole body of visible or tangible objects) are neither visible nor tangible. Our information, therefore, must here also be derived from reduction to the sphere of the senses. But the most radical and primary difference of formation depends on the abundance or scarcity of matter within the same space or dimensions. For the other formations which regard the dissimilarity of the parts contained in the same body, and their collocation and position, are secondary in comparison with the former. Let the required nature then be the expansion or coherence of matter in different bodies, or the quantity of matter relative to the dimensions of each. For there is nothing in nature more true than the twofold proposition--that nothing proceeds from nothing and that nothing is reduced to nothing, but that the quantum, or sum total of matter, is constant, and is neither increased nor diminished. Nor is it less true, that out of this given quantity of matter, there is a greater or less quantity, contained within the same space or dimensions according to the difference of bodies; as, for instance, water contains more than air. So that if any one were to assert that a given content of water can be changed into an equal content of air, it is the same as if he were to assert that something can be reduced into nothing. On the contrary, if any one were to assert that a given content of air can be changed into an equal content of water, it is the same as if he were to assert that something can proceed from nothing. From this abundance or scarcity of matter are properly derived the notions of density and rarity, which are taken in various and promiscuous senses. This third assertion may be considered as being also sufficiently certain; namely, that the greater or less quantity of matter in this or that body, may, by comparison, be reduced to calculation, and exact, or nearly exact, proportion. Thus, if one should say that there is such an accumulation of matter in a given quantity of gold, that it would require twenty-one times the quantity in dimension of spirits of wine, to make up the same quantity of matter, it would not be far from the truth. The accumulation of matter, however, and its relative quantity, are rendered sensible by weight; for weight is proportionate to the quantity of matter, as regards the parts of a tangible substance, but spirit and its quantity of matter are not to be computed by weight, which spirit rather diminishes than augments.