_Seleucus_ came down with a powerful army into _Cappadocia_, and joining the confederate forces, fought _Antigonus_ in _Phrygia_ and flew him, and seized his kingdom, _An. Nabonass._ 447. After which _Seleucus_ built _Antioch_, _Seleucia_, _Laodicea_, _Apamea_, _Berrhaea_, _Edessa_, and other cities in _Syria_ and _Asia_; and in them granted the _Jews_ equal privileges with the _Greeks_. _Demetrius_ the son of _Antigonus_ retained but a small part of his father's dominions, and at length lost _Cyprus_ to _Ptolemy_; but afterwards killing _Alexander_, the son and successor of _Cassander_ king of _Macedon_, he seized his kingdom, _An. Nabonass._ 454. Sometime after, preparing a very great army to recover his father's dominions in _Asia_; _Seleucus_, _Ptolemy_, _Lysimachus_ and _Pyrrhus_ king of _Epirus_, combined against him; and _Pyrrhus_ invading _Macedon_, corrupted the army of _Demetrius_, put him to flight, seized his kingdom, and shared it with _Lysimachus_. After seven months, _Lysimachus_ beating _Pyrrhus_, took _Macedon_ from him, and held it five years and a half, uniting the kingdoms of _Macedon_ and _Thrace_. _Lysimachus_ in his wars with _Antigonus_ and _Demetrius_, had taken from them _Caria_, _Lydia_, and _Phrygia_; and had a treasury in _Pergamus_, a castle on the top of a conical hill in _Phrygia_, by the river _Caicus_, the custody of which he had committed to one _Philetaerus_, who was at first faithful to him, but in the last year of his reign revolted. For _Lysimachus_, having at the instigation of his wife _Arsinoe_, slain first his own son _Agathocles_, and then several that lamented him; the wife of _Agathocles_ fled with her children and brothers, and some others of their friends, and sollicited _Seleucus_ to make war upon _Lysimachus_; whereupon _Philetaerus_ also, who grieved at the death of _Agathocles_, and was accused thereof by _Arsinoe_, took up arms, and sided with _Seleucus_. On this occasion _Seleucus_ and _Lysimachus_ met and fought in _Phrygia_; and _Lysimachus_ being slain in the battel, lost his kingdom to _Seleucus_, _An. Nabonass._ 465. Thus the Empire of the _Greeks_, which at first brake into four kingdoms, became now reduced into two notable ones, henceforward called by _Daniel_ the kings of the _South_ and _North_. For _Ptolemy_ now reigned over _Egypt_, _Lybia_, _Ethiopia_, _Arabia_, _Phoenicia_, _Coelosyria_, and _Cyprus_; and _Seleucus_, having united three of the four kingdoms, had a dominion scarce inferior to that of the _Persian_ Empire, conquered by _Alexander_ the great. All which is thus represented by _Daniel_:[2] _And the king of the_ South [_Ptolemy_] _shall be strong, and one of his Princes_ [_Seleucus_, one of _Alexander_'s Princes] _shall be strong above him, and have dominion; his dominion shall be a great dominion_.