When this malignant fever takes place in all its virulence, its consequences are the most disastrous; the symptoms are violent and without gradation, and the blood is heated to an increased degree beyond what is experienced in Europe; the ninth day is generally decisive, and this is a crisis that requires the most vigilant attention and care over the patient. I speak this from personal experience. In consequence of the fatigues I underwent in the Rio Pongo, and other rivers, and having been for several days and nights exposed to an open sea, and to torrents of rain upon land, I was seized with this dreadful disorder, although I had enjoyed an uninterrupted state of good health before, and on my arrival at the colony of Sierra Leone was unable to support myself on shore; and had it not been for the kind attention and skilful prescriptions of Dr. Robson of that colony, with the friendly offices of Captain Brown, I should, in all probability, at this stage have finished my travels and existence together. Dysenteries frequently follow this fever, which are of a very fatal tendency, and sometimes the flux is unattended by fever. This disease is not uncommon in persons otherwise healthy, but it is productive of great debility, which requires a careful regimen; if it continues to a protracted period, its consequences are often fatal. In my own case, a dysentery followed the fever, and reduced me to a mere skeleton. The dry belly-ache is another dangerous disease, accompanied by general languor, a decrease of appetite, a viscous expectoration, and fixed pain in the stomach. Opium is considered an efficacious medicine in this disease, and is administered with great perseverance, accompanied by frequent fomentations. An infusion of ginger drank in the morning has frequently good effects. Flannel assists excretion, and is found beneficial. _Tetanos_ is also another disease peculiar to Africa, and is a kind of spasm and convulsive contraction, for which opium is the usual remedy. The Guinea worm is another disease among the natives, which is productive of tumours upon the body and limbs, productive of great pain, and is a contagious disease. This, however, is a subject without my province, and which has been ably treated upon by gentlemen, whose profession fully qualified them for the investigation. In addition to the many valuable treatises upon tropical diseases, from high authority, I would recommend Dr. Winterbottom's publication to the reader, as, embracing highly important local information upon the diseases of the Windward Coast.