=2. Changes in the breasts.= These also occur early. The breasts ordinarily increase in size and firmness, and many women complain of throbbing, tingling or pricking sensations and a feeling of tension and fullness. The breasts may be so tender that even slight pressure is painful. The nipples are larger and more prominent, while both they and the surrounding areolæ grow darker. The veins under the skin are more apparent and the glands of Montgomery larger. If in addition to these symptoms it is possible to express a pale yellowish fluid from the nipples of a woman who has not had children, pregnancy may be strongly suspected. But practically all of these symptoms may be due to causes other than pregnancy, and, in the case of a woman who has borne children, milk may be present in the breasts for months, or even years, after the birth of a child. =3. “Morning sickness,”= as the name suggests, is nausea, sometimes accompanied by vomiting, from which many pregnant women suffer immediately upon arising in the morning. It varies in severity from a mild attack when the patient first lifts her head to repeated and severe recurrences during the day, and even into the night. More frequently, however, the discomfort passes off in a few hours. When the vomiting persists, it is termed “pernicious vomiting” and is usually accepted as a possible symptom of a reflex, toxic or neurotic condition, all of which will be discussed with the complications of pregnancy. Morning sickness may begin immediately after conception, but sets in as a rule about the sixth week and continues until the third or fourth month. It occurs in about half of all pregnancies and is particularly common among women pregnant for the first time. But on the other hand, it must be borne in mind that many non-pregnant women suffer from nausea in the morning; many women go throughout the entire period of gestation without any such disturbance, while others are entirely comfortable in the morning and nauseated only during the latter part of the day. =4. Frequent micturition.= There is usually a desire to void urine frequently during the first three or four months of pregnancy, after which the tendency disappears, but recurs during the later months. The inclination may be due in part to nervousness, but is largely caused by pressure exerted by the enlarging uterus upon the bladder, and not to any functional disturbance of the kidneys, as is sometimes believed. Pressure on the outside of the bladder gives much the same sensation as is experienced when the bladder is distended with urine. After the uterus rises from the pelvic cavity into the abdomen, it no longer crowds the bladder, until it drops during the last month or six weeks, when it again presses upon this organ and cause a desire to void.