body, showing that the poisonous products of these processes have passed through the kidneys and been eliminated. Thus we find albuminuria and casts, and even signs of a serious inflammation of the kidneys, in different infectious diseases, and even after tonsillitis; also after other toxic conditions caused by the secretion of toxic products in the body from certain ductless glands, such as the sexual glands during puberty and the thyroid gland in Graves’s disease. Likewise in certain diseases where waste products of metabolism cause uric acid to be formed in large quantities, as also in diabetes, where a quantity of other toxic products, besides uric acid, are produced. From the foregoing it is only natural to expect that different toxic products which are introduced into the organism from without, either in the food or in the drink, or which result from the decomposition of meat and alcohol and other stimulants, will also, for the most part, be eliminated by the kidneys, especially with a dilatory performance of the other disintoxicating organs. When passing in large quantities, or sometimes even in smaller numbers, they may be able to irritate the fine epithelia of the tabula epithelia and also those of the glomeruli, and produce casts (hyaline ones especially) and albuminuria. After large quantities of alcohol such a condition can even become permanent if the other toxin-secreting organs are sluggish. In his experiments on animals Penzoldt has produced albuminuria by means of English mustard, pepper, and particularly radishes, and still more so after black tea. Gunzburg noted this also in a boy of 13, and Roth in a child of 3½, in both cases after the use of black tea. Albuminuria and casts can frequently be observed after the administration of drugs in degrees varying according to the toxicity of the drugs. We have published a case in which even epithelial cells of the kidneys, single and in casts, as well as blood-casts in quantities, have been found after an administration of chloride of potassium. Luttje found casts in 33 cases out of 207, and in 92 of these albuminuria, after the administration of salicylates, and he issues a warning against their continual usage. That the same occurrence has also been observed after the use of other poisonous drugs such as mercury, chloroform, etc., will only appear to us as natural.