On chloroform and other anæsthetics: their action and administrationSnow, John
History
On chloroform and other anæsthetics: their action and administration
Snow, John
Anesthetics; Chloroform; Snow, John, 1813-1858
At the examination of the body, the cartilages of the ribs were found to
be ossified. The heart and lungs were perfectly healthy, but the lungs
were in a congested condition. There was an extravasation of blood in
the spinal muscles, and a little blood in the spinal canal, in what part
or between what structures is not stated.[111]
_Case 40_ occurred in the Lock Hospital, London, in May 1854. Walter
Hollis, a tailor, aged eighteen, had been under treatment for sores
within the prepuce, and these having healed, he was about to undergo the
operation for congenital phymosis. He had been of dissolute habits, and
exhibited a pale cachectic appearance.
“The inhaler used was a simple mouth-piece by which the nostrils are
left uncovered. About two drachms of the fluid were poured into the
instrument. After about six minutes inhalation, insensibility seemed to
be coming on, and at this moment the pulse was ascertained to be of good
volume. Nothing whatever had occurred to indicate the impending danger,
when, after a few more inhalations, the pulse suddenly failed, became
quite imperceptible, and the countenance assumed a pale and leaden hue.
The inhalation was immediately stopped, and attempts to resuscitate, by
means of striking the chest sharply with a wet towel, applying ammonia
to the nostrils, and by artificial respiration, were at once commenced.
These were employed for three or four minutes before any signs of life
were perceived; but, subsequently, the pulse was again to be felt, and
spontaneous respiration was renewed. Artificial respiration was desisted
from on the occurrence of these signs of returning life, and for upwards
of ten minutes the chest continued to fill regularly, and the pulse beat
at a rate of from 40 to 50 in the minute; the countenance of the patient
also much improved, and even assumed a slight flush. After the
expiration of, perhaps, a little more than ten minutes, however, these
indications of returning vitality again disappeared, the pulse and
respiratory efforts simultaneously ceased, and the countenance became
deathlike. Artificial respiration and the other means were again
adopted, but this time without the slightest success.... Post-mortem
examination on the next day shewed great venous congestion within the
cranium; the lungs were also somewhat congested. The heart was slightly
enlarged, and the ventricular parietes were thinned; in the muscular
fibres the microscope detected decided fatty degeneration. The blood was
universally fluid.”[112]
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