_Raising depressed Portions of Skull._ In Dec. 1848, I administered chloroform to a gentleman in Norfolk, aged sixty-two, on whom the late Mr. Aston Key operated. The patient had been thrown from his horse four years previously, and probably kicked whilst on the ground. He believed that he did not lose his consciousness. There was a considerable depression of a portion of the right parietal bone, near its upper and posterior angle; but there were no symptoms of cerebral pressure or irritation for two years after the accident; but at that time he fell from his seat in some kind of fit, after which he had partial paralysis of the left arm, impaired vision, and a melancholy or apathetic state of mind. He was also subject to attacks of real or apparent suspension of breathing, and to occasional attacks of vomiting. His ordinary medical attendant, Dr. Bell of Aylsham, objected to the chloroform, on account of feeble and irregular action of the heart, in addition to the above symptoms. The patient, however, became gradually insensible, without any unfavourable symptoms. After making incisions in the scalp, Mr. Key sawed out a good sized piece of the parietal bone with Hey’s saw. The insensibility was kept up gently during the operation, which lasted above half an hour. There was pus under the bone, and the dura mater was diseased, and gave way during the operation. Mr. Key immediately expressed a bad opinion of the case. The patient recovered his consciousness in about a quarter of an hour, and in a little time was in the perfect enjoyment of all his faculties, being very cheerful, and in a totally different state from the one of apathy and almost unconsciousness, in which he appeared when we first saw him. He was attacked with inflammation of the brain on the third day, and died on the fifth. In May 1855, I administered chloroform in St. George’s Hospital to a young man who had been kicked by a horse. The frontal bone above the right eye was driven in to a good depth, and a little of the brain had escaped. Mr. Cæsar Hawkins cut a piece from the frontal bone, just above the depressed portion, with the bone forceps, to enable him to introduce the elevator. The depressed portion being quite loose, was removed, together with the roof of the orbit. The youth was partially comatose before chloroform was given, but made a resistance to the operation. A week after the operation, when I saw him, he was conscious, but feverish, and he died a week or two later. Mr. Bowman, on one occasion, made an incision over the frontal sinus in a gentleman; and made an aperture in the outer table of the frontal bone, which gave exit to a quantity of pus which had been formed in the sinus. In the summer of 1847 the late Mr. Liston performed a similar operation on a lady, the patient of Dr. Locock, who was present. I exhibited sulphuric ether on that occasion.