On chloroform and other anæsthetics: their action and administrationSnow, John
History
On chloroform and other anæsthetics: their action and administration
Snow, John
Anesthetics; Chloroform; Snow, John, 1813-1858
There is occasionally a feeble state of pulse with a feeling of
faintness as the effects of the chloroform subside, and in two or three
cases in which the patient was in a sitting posture, positive syncope
occurred, which, however, was promptly removed by the horizontal
position. The persons most liable to a feeling of faintness after
chloroform, are those who are subject to syncope from slight causes.
_Action of Chloroform on the Nervous System._ Chloroform, when inhaled,
immediately reaches every part of the nervous system through the
circulation, and it acts on every part of that system from the first, as
a careful observation of the symptoms proves. It does not, however, act
equally on all parts of the nervous system, according to the quantity
which is absorbed; some parts of that system have their functions
entirely, or almost, suspended, whilst others are but little under the
influence of the vapour, and it is owing to this fact that the most
severe pain may be prevented without danger. M. Flourens made the
following remarks respecting the action of sulphuric ether, and they
apply equally well to the effects of chloroform, when it is inhaled
gradually: “Under the action of ether, the nervous centres lose their
powers in regular succession—first, the cerebral lobes lose theirs,
viz., the intellect; next, the cerebellum loses its, viz., the power of
regulating locomotion; thirdly, the spinal marrow loses the principle of
sensitiveness and of motion; the medulla oblongata still retains its
functions, and the animal continues to live: with loss of power in the
medulla oblongata, life is lost.”[51] I may add, that after the
breathing has ceased, from the loss of power of the medulla oblongata,
the ganglionic nerves still perform their functions, and the heart and
intestines continue to move for a time, often with vigour.
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