10:35 no movements no movements no movements 10:40 no movements no movements no movements 10:45 no movements no movements no movements 10:50 no movements no movements no movements 10:55 no movements no movements no movements 11:00 no movements no movements no movements 11:15 no movements no movements no movements 11:30 no movements no movements no movements 11:45 no movements no movements no movements 11:50 no movements no movements no movements Thus here also, as in the case of LiCl and CaCl_{2}, there are produced effects in mixtures of NaCl and CaCl_{2} which cannot be brought about by either salt alone. The presence of CaCl_{2} seems to inhibit the movements which are first present in a loop placed in NaCl solution. When added in small quantities, _e.g._, not more than 10 c.c. m/6 CaCl_{2} to 50 c.c. m/6 NaCl, it produces after an interval of 10-15 minutes very violent movements such as are never seen in pure NaCl solution nor in pure CaCl_{2}. When, however, it is added in greater proportion than this, e.g., 20 or more c.c. CaCl_{2} to 50 c.c. NaCl, all movements are stopped. The explanation of this is no more clear than the similar occurrence in mixtures of LiCl and CaCl_{2}. If a loop be placed in a mixture of LiCl and NaCl in equal parts, movements appear such as are seen in pure NaCl, but do not persist for so long a time. In the mixture of these two salts no such result is obtained as has been described in mixtures of LiCl and CaCl_{2} or of NaCl and CaCl_{2}. Mixtures of CaCl_{2} and MgCl_{2} also produce no such movements. In these few salts it seems to be a mixture of chlorides of a monovalent with a bivalent metal which produces the extreme activity of the loop, while mixtures of chlorides of two monovalent metals or of two bivalent metals do not bring this about. FOOTNOTES: [61] MACCALLUM, J. B.: University of California Publications, Physiology, Vol. II, 1905, p. 47. CHAPTER VIII. The Effect on the Intestine of Intravenous Saline Infusions. It has been frequently observed that a quantity of fluid enters the intestine during the intravenous injection of normal salt solution. According to Dastre and Loye,[62] the fluid injected into the veins is largely eliminated by the kidneys, although these organs may be assisted in this function by the salivary glands and intestine. These authors have found fluid to be present in the intestine of rabbits as well as in the pleural and peritoneal cavities after the injection of large quantities of salt solution. They state that in such an intravenous injection diarrhœa often results which may be so pronounced that a clear fluid emerges from the rectum. Knoll[63] also mentions the production of diarrhœa by the injection of large quantities of NaCl solution.