Quantitative estimations of the sugar in the intestinal juice in this case were made. The amount varied between 0.2 and 0.3%. I have not attempted to ascertain the total quantity of sugar which may be obtained from the intestinal juice by continued infusion of salt solution. In the case of the urine, Bock and Hoffmann made such determinations and found that the kidney eliminated in one case 1.632 g. and in another case 2.04 g. sugar. M. H. Fischer found that the concentration of sugar in the urine of a rabbit rarely exceeds 0.25% after infusion of m/6 NaCl. Thus the intestine eliminates sugar in a way that entirely resembles its elimination by the kidneys. The sugar appears in the blood after the infusion of a certain amount of the salt solution and is excreted by the kidney. If the kidneys are removed, it is excreted by the intestine. But even when the kidneys are intact there is a certain amount of sugar excreted by the intestine, just as a part of the fluid injected is eliminated by the intestine when the kidneys are still active. As shown in the following experiment, the sugar appears both in the intestinal juice and in the urine. The quantity of sugar, however, is greater in the urine than in the intestinal juice. In the urine it was found to be about 0.2%, in the intestinal juice considerably less. The quantity of urine also is greater than the quantity of intestinal juice. Therefore the greater proportion of the sugar is excreted by the kidneys. Rabbit--Cannula placed in bladder. Kidneys intact. Cannula in loop of upper part of small intestine 35 cm. long. Loop contained 4.2 c.c. fluid; no sugar. Intestinal juice. Urine. NaCl m/6 /---------------------\/----------------------\ Time. injected. Quantity. Sugar Quantity. Sugar examination. examination. 9:45 Infusion Loop emp’d, No sugar. Bladder No sugar. begun. 4.2 c.c. emptied, 5 c.c. 10:15 5 c.c. 1.8 c.c. ” ” 0.0 10:45 50 ” 2.2 ” ” ” 0.0 11:15 80 ” 2.9 ” ” ” 4.0 c.c. No sugar. 11:45 92 ” 3.8 ” ” ” 15.0 Sugar present. 12:15 120 ” 6.6 ” Sugar present. 38.0 Much sugar. 12:45 150 ” 7.8 ” ” ” 40.0 ” ” ----- 497 ”