On the origin of inflammation of the veins: and of the causes, consequences, and treatment of purulent depositsLee, Henry, M.D.
History
On the origin of inflammation of the veins: and of the causes, consequences, and treatment of purulent deposits
Lee, Henry, M.D.
Blood; Veins -- Diseases
This disposition of the blood to separate into its constituent parts is
evinced in a very marked degree in one class of secondary affections.
Extensive effusions of serum, lymph, and pus, mixed in different
proportions, will take place in the serous cavities of the body, and
become infiltrated in the cellular membrane, accompanied with very
slight indications of inflammatory action. The colouring matter of the
blood will also sometimes become effused with its other parts; but when
this is the case, the blood will be found to have lost its coagulating
power: in this respect presenting a direct contrast to the effusion
from a healthy wounded vessel. The lymph deposited will be found lying
in unorganized flakes, wanting its usual adhesive properties, and
very slightly attached to parts, presenting little or no increased
vascularity. The rapid manner in which these depositions take place,
shows that they are separated from the blood without undergoing any
very elaborate process. In this condition of the system, any organ
upon which the disease falls, may rapidly become disorganized, or may
readily mortify; and, after death, a tendency to rapid decomposition
will be manifested. The veins on the surface of the body may frequently
be traced as dark blue lines, as though the skin covering them were
stained by the colouring matter of the blood. The lungs and other
organs may, under these circumstances, be found in every grade of
disorganization, till they present all the characteristics of gangrene:
even the peculiar fetor which accompanies mortification of the lung,
will, in some instances, be present. A tendency to the formation of
petechial spots may also be observed in different parts; and even
the organs which do not appear to have been the peculiar seat of the
disease, will be found to have lost their consistency, and to break
down upon comparatively slight pressure.
Mr. Hunter found, that in proportion as the blood retained the power
of coagulation, it had the power of resisting putrefaction; and
conversely, we observe that, in this class of cases, the deficiency
of the former is accompanied in a marked manner by the absence of the
latter.
The two conditions of the blood which have now been mentioned,
appear to bear a direct relation to the two classes of post-mortem
appearances, observed in cases of secondary inflammations: the first
being generally connected with congestion of different organs during
the first stages of the disease, the second with extensive effusions,
accompanied with comparatively little vascularity.
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