When the slough separated, the surface of the external oblique muscle was left as clean as if recently dissected. The skin was undermined for some extent, and no attempt was apparently being made to limit the progress of the disease, by the effusion of lymph. Fresh portions of cellular tissue consequently became affected, and the whole surface ultimately exposed was full six inches in diameter. _Sept._ 25th. Complained of some pain in the chest and upper part of the abdomen; has a constant short cough; perspires very freely. 26th. The pulse has become weaker, but remains of the same frequency (130). It communicates a peculiar jerking sensation to the finger. 28th. Pulse 96, weaker; slight diarrhoea; he vomited several times during the day. 29th. Restless, with delirium. 30th. Passed another restless night, but became better in the course of the day; his appetite returned. _Oct._ 5th. His appetite again failed; complained of a sense of distension in the abdomen. 8th. An abscess was discovered at the lower and back part of the right leg; the skin over this presented various shades of yellow and brown, giving the appearance of having been extensively bruised. About two ounces of discoloured pus were evacuated, together with a considerable quantity of grumous blood. 10th. Has much improved since the last report; the wound discharges dark semi-coagulated blood. 13th. A second abscess now presented itself in the same leg, and the skin covering it assumed the same discoloured appearance as in the first instance. When opened, it discharged dark-coloured semi-coagulated blood with the matter. He now rapidly improved in health, and at length perfectly recovered. CASE XXVIII. Samuel Todd, æt. 58, fell from a wagon fifteen miles from town, and was brought up in an open cart, during a sharp frost. There was a compound fracture of the left leg. Two days afterwards, he suffered from cellular inflammation around the wound. On the 24th day, he had a slight rigor, and complained of slight stiffness in the right shoulder. He ate and drank well till within two days of his death, which took place on the thirty-fourth day. _Post-mortem appearances._ Both lungs contained secondary abscesses, in various stages of formation. The left external iliac and common femoral veins were blocked up with firm coagula, and confined by these was a quantity of purulent-looking fluid; an adherent layer could, for some distance, be peeled off the internal surface of these vessels.