M. Grandmaison, who had set out a whole month earlier, had stopped at Canelos no longer than was necessary to make needful preparations for his daughter and her attendants. Then he had immediately pushed on toward the vessel, to still keep in advance, and arrange matters for her convenience at the next station to which she would arrive. Hardly had he left Canelos, when the small-pox, a disease which in those regions is particularly fatal, broke out, and in one week swept off one-half of the inhabitants, and so alarmed the rest, that they deserted the place, and plunged into the wilderness. Consequently, when Madame Godin reached the place with her party, she found, to her dismay, only two Indians remaining, whom the fury of the plague had spared; and, moreover, not the slightest preparation either for her reception, or her furtherance on her journey. This was the first considerable mishap which befell her, and which might have served to forewarn her of the greater sufferings which she was to encounter. A second followed shortly after. The thirty Indians who thus far had carried the baggage, and had received their pay in advance, suddenly absconded, whether from fear of the epidemic, or that they fancied, having never seen a vessel except at a distance, that they were to be compelled to go on board one, and be carried away. There stood, then, the deserted and disappointed company, overwhelmed, and knowing not what course to take, or how to help themselves. The safest course would have been to leave all their baggage to its fate, and return back the way they came; but the longing of Madame Godin for her beloved husband, from whom she had now been separated so many years, gave her courage to bid defiance to all the hinderances which lay in her way, and even to attempt impossibilities. She set herself, therefore, to persuade the two Indians above mentioned to construct a boat, and, by means of it, to take her and her company to Andoas, another place about twelve days' journey distant. They willingly complied, receiving their pay in advance. The boat was got ready; and all the party embarked in it under the management of the two Indians. After they had run safely two days' journey down the stream, they drew up to the bank to pass the night on shore. Here the treacherous Indians took the opportunity, while the weary company slept, to run away; and, when the travellers awoke next morning, they were nowhere to be found. This was a new and unforeseen calamity, by which their future progress was rendered greatly more hazardous.