But the terrible effects wrought upon the eastern episcopate by the Arian assault had not been finally overcome. The next attack upon the Person of our Lord proceeded from the eloquent Syrian, Nestorius, who had been put in the see of Constantinople. It required all the energy of Pope Celestine and the patriarch Cyril of Alexandria, to overcome that heresy which still attacked the Incarnation, and was supported by court favour at the eastern capital, and the jealousy of its emperor for his bishop. It is remarkable that the First Council at Ephesus, in 431, should have been followed by a Second Council at the same place in 447. This second Council was, so far as its convocation and its constitution went, regularly entitled to be a General Council. Its decree was in favour of an opposite heresy to that of Nestorius, on the same subject of our Lord’s Person, and its originator was the monk Eutyches, in high repute at the head of a monastery at Constantinople. The Council after its completion was rejected, and the heresy overthrown, by the single arm of St. Leo the Great. The whole Church at Chalcedon accepted his act and acknowledged his Primacy. But this Monophysite heresy had driven its roots deep into the Greek mind. During two hundred years, to the time of Mohammed himself, its effects may be traced, corrupting the unity of belief in the eastern patriarchates, encouraging perpetual party spirit, breaking constantly the succession of bishops in the hierarchy. In the time of St. Leo, the patriarch Proterius, who succeeded the deposed Dioscorus, was murdered by the Monophysite faction. A few years later the bishop of Constantinople used this heresy for the purpose of exalting his see against Rome, which had just been deprived of its emperor, and its government left in the hand of barbarians, who were also heretics. Thus supported by imperial power, Acacius brought about a schism which lasted for thirty-five years. The resistance of seven Popes, the last of whom, Hormisdas, obtained the full result which his predecessors had sought for, frustrated this second century of Byzantine aggression upon the faith and government of the Church.