Pharmacologia: Fourth American, from the Seventh London EditionParis, John Ayrton
Science
Pharmacologia: Fourth American, from the Seventh London Edition
Paris, John Ayrton
Pharmacognosy; Pharmacology; Pharmacy
QUALITIES. _Form_, small feathery crystals of a brilliant white colour,
which are not brittle, but possess a kind of ductility and elasticity,
and, on being rubbed in a mortar, assume the consistence of paste.
_Odour._ As generally met with, it possesses a peculiar aromatic smell,
but this depends upon the oily matter which adheres to it, for Mr. Guise
informs us, that on dissolving the benzoic acid in as little alcohol as
possible, filtering the solution, and precipitating by water, the acid
will be obtained pure, and void of smell, the odorous oil remaining
dissolved in the spirit. _Taste_, rather acrid and sour; _Specific
Gravity_, ·667. It is not altered by exposure to air. SOLUBILITY. Four
hundred parts of cold water dissolve but one, although the same quantity
of boiling water dissolves twenty parts, nineteen of which separate on
cooling; in alcohol it is soluble in a much greater proportion.
MEDICINAL USES. It is said to be stimulant and expectorant; in certain
cases of tracheal irritation, a pill, composed of two grains of Benzoic
acid, and three of Extract of Poppy, has been found serviceable.
OFFICINAL PREPARATIONS. _Tinctura Camphoræ Composita_, L.D. _Tinct: Opii
Ammoniat:_ E. IMPURITIES. The crystals ought not to be discoloured; they
should dissolve without residuum in alcohol, and when subjected to heat,
ought to be entirely volatilized.
Although this acid is commonly procured from the resinous substance
called Benzoin, yet it exists extensively in other vegetable, and in
some animal substances. In the Tonca bean (_Dipterix odorata_) it is
frequently to be seen beautifully crystallized on its surface. It exists
also in vanello; cinnamon; cloves; ambergris; in the urine of children,
and sometimes in that of adults, and always in that of quadrupeds living
on grass and hay.
ACIDUM CITRICUM. (_Crystalli_) Citric Acid.
_Concrete Acid of Lemons._
QUALITIES. _Form_, crystals which are right rhombic prisms, white,
semi-transparent, and persistent. _Taste_, extremely acid, almost
caustic. SOLUBILITY, f℥j of cold water dissolves ʒx, but of boiling,
℥ij. ʒx of the crystals dissolved in a pint of water, are about
equivalent to one pint of lemon juice, the solution however if kept is
liable to spontaneous decomposition. The following table of equivalents
may be found of practical use; the author is aware that they do not
exactly agree with the proportions of Dr. Haygarth, but they are the
results of careful and repeated experiments, and as such they are
submitted with confidence.
EQUIVALENT PROPORTIONS OF CONCRETE CITRIC ACID AND LEMON JUICE,
NECESSARY FOR THE NEUTRALIZATION OF ALKALINE SALTS.
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