Pharmacologia: Fourth American, from the Seventh London EditionParis, John Ayrton
Science
Pharmacologia: Fourth American, from the Seventh London Edition
Paris, John Ayrton
Pharmacognosy; Pharmacology; Pharmacy
production of a blue colour when supersaturated with ammonia. The yellow
tinge of the acid usually met with in commerce, may depend either upon
the presence of iron, vegetable extractive, or a small portion of
chlorine. This latter body may be recognised by the odour, or by its
power of dissolving gold leaf.
ACIDUM NITRICUM. L.E.D. _Nitric Acid._
Aqua Fortis.
QUALITIES. A limpid liquid of the specific gravity 1·500, a fluid-ounce
of which is equal to about 11 drachms, 1 scruple by weight, and ought to
decompose of pure limestone an ounce; it emits white fumes of a
suffocating odour. _Taste_, extremely acid; it is highly corrosive, and
tinges the skin indelibly yellow; an effect which is considerably
heightened by the subsequent application of an alkali, so that these
agents afford the means of detecting minute portions of animal matter,
and were ingeniously employed for such an object by Mr. Hatchett.
CHEMICAL COMPOSITION. When of the specific gravity 1·500, it contains
74·895 per cent. of dry acid; (whose ultimate elements are one portion
of nitrogen and five of oxygen) the compliment 25·105 parts is water. It
is decomposed with violent action by all combustibles, and when mixed
with volatile oils, it causes their inflammation. It boils at 210°, and
when its specific gravity is below 1·4, it is strengthened, when
stronger than 1·45 it is weakened by ebullition. USES. It is principally
employed as a pharmaceutical agent; _viz._ for the preparation of
_Argenti Nitras_; _Liquor Ferri Alkalini_; _Hydrargyri Nitri-co-oxydum_;
_Spiritus Etheris Nitrici_; and _Unguentum Hydrargyri Nitratis_. As an
escharotic it has been frequently employed for the destruction of
tumours, and is certainly of value where an immediate destruction of
diseased parts is required. The method of using the strong nitric acid
in such cases is to smear all the sound parts in the immediate vicinity
of the ulcer with _Ung: Resin: Nig:_ and then to apply pledgets of lint
firmly upon the ulcer for a few seconds, by which the whole surface will
be deadened, and a deep slough remain, underneath which healthy
suppuration and granulations will ensue.[352] ADULTERATIONS. _Sulphuric
acid_ may be detected by a precipitate being produced on the addition of
nitrate of baryta; in the application however of this test, Mr. Hume has
shewn that unless this as well as the nitric acid be diluted, a
precipitate will occur, although sulphuric acid should not be present; a
circumstance which depends upon the barytic salt yielding its water of
solution to the acid under examination, and becoming insoluble.
_Muriatic acid_ is discovered by nitrate of silver, affording a
precipitate at first white, but becoming coloured by exposure to light;
the nitric acid ought to be perfectly colourless, but to preserve it in
such a state it must be closely stopped, and kept in a dark place, or it
will soon be converted into nitrous acid.
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