Pharmacologia: Fourth American, from the Seventh London EditionParis, John Ayrton
Science
Pharmacologia: Fourth American, from the Seventh London Edition
Paris, John Ayrton
Pharmacognosy; Pharmacology; Pharmacy
QUALITIES. _Form_, octohedral crystals, whose sides are equilateral
triangles; they are slightly efflorescent. _Taste_, sweet, rough, and
acidulous. CHEMICAL COMPOSITION. It is a triple, or sometimes a
quadruple salt, with excess of acid, consisting of sulphuric acid and
alumina, with potass, or ammonia, or frequently both of them; the nature
of the alkali however does not in the least appear to affect the
properties of alum, although it produces a crystallographic
modification; for where potass is present the summit of the crystal will
exhibit a truncation. Dr. Ure has lately produced alum with soda, and
the combination differs from common alum only in its greater degree of
solubility, a property which at once recommends it to the attention of
the pharmaceutist and physician. SOLUBILITY. A fluid-ounce of cold water
dissolves 30 grains, but if boiling four drachms; it is insoluble in
alcohol. INCOMPATIBLE SUBSTANCES. _Alkalies_ and _alkaline salts_, after
neutralizing the excess of acid, precipitate the alumine. It is also
decomposed by _carbonate_ and _muriate of ammonia_, _carbonate of
magnesia_, and _tartrate of potass_, by _lime-water_, _acetate of lead_,
and _the salts of mercury_, as well as by many vegetable and animal
substances, especially _galls_ and _kino_. It is on this account very
injudicious to combine alum with any vegetable astringent with a view to
encrease its virtues; thus the “_Pulvis Sulphatis Aluminæ compositus_”
of the Edinburgh college, is less powerful than any of the ingredients
of which it is composed; and the addition of alum to the decoction of
bark, undoubtedly diminishes its efficacy as an astringent injection.
MEDICINAL USES. Alum is internally a powerful astringent, in hæmorrhages
and inordinate fluxes, and is externally useful for repellent and
astringent lotions, gargles, and collyria. Dioscorides and Hippocrates
praised its effects as a lotion in various kinds of ulcers, and
particularly in sores of the mouth, and in spongy, swelled gums.
Van-Helmont was the first person who employed alum in uterine
hemorrhage, and the success of the practice very considerably enhanced
his reputation. _Boerhaave’s_ astringent powder for the ague consisted
of _Alum_ and _Nutmeg_ with the addition of _Armenian bole_. DOSE, gr.
x. In large doses it is liable to excite nausea, and to act upon the
bowels. Nutmeg or some aromatic should therefore be joined with it.
FORMS OF EXHIBITION. In solution, or in substance made into pills with
extract; (_Form: 53, 56_,) it is sometimes given with advantage in the
form of whey (_Alum-whey—Serum Aluminosum_) made by boiling ʒij with a
pint of milk, and then straining, the dose of which is a wine glass
full; (_Form; 54._) By briskly agitating a drachm of alum with the white
of an egg, a coagulum is formed, (_Alum curd of Riverius_; _Albumen.
Aluminosum_) which is serviceable in some species of ophthalmia, when
applied between two pieces of thin linen rag.[365] As alum is not
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