Pharmacologia: Fourth American, from the Seventh London EditionParis, John Ayrton
Science
Pharmacologia: Fourth American, from the Seventh London Edition
Paris, John Ayrton
Pharmacognosy; Pharmacology; Pharmacy
On the other hand, substances may be medically inconsistent, which are
chemically compatible, as I shall have frequent opportunities of
exemplifying. The stomach has a chemical code of its own, by which the
usual affinities of bodies are frequently modified, often suspended, and
sometimes entirely subverted; this truth is illustrated in a very
striking manner by the interesting experiments of M. Drouard, who found
that Copper, swallowed in its metallic state, was not rendered poisonous
by meeting with oils, or fatty bodies; nor even with _Vinegar_, in the
digestive organs. Other bodies, on the contrary, seem to possess the
same habitudes in the stomach as in the laboratory, and are alike
influenced in both situations by the chemical action of various bodies,
many examples of which are to be found under the consideration of the
influence which solubility exerts upon the medicinal activity of
substances; so again, acidity in the stomach is neutralized by
_Alkalies_, and if a _Carbonate_ be employed for that purpose, we have a
copious disengagement of _Carbonic acid gas_, which has been frequently
very distressing to the patient; lastly, many bodies taken into the
stomach undergo decompositions and changes _in transitu_, independent of
any play of chemical affinities from the hidden powers of digestion,
some of which we are enabled to appreciate, and they will accordingly
form a subject of investigation in the course of the present work.
The powers of the stomach would seem to consist in decomposing the
_Ingesta_, and reducing them into simpler forms, rather than in
complicating them, by favouring new combinations.
But every rational physician must feel in its full force, the absurdity
of expecting to account for the phænomena of life upon principles
deduced from the analogies of inert matter, and we therefore find that
the most intelligent physiologists of modern times have been anxious to
discourage the attempt, and to deprecate its folly. Sir Gilbert Blane,
in his luminous work on MEDICAL LOGIC, when speaking of the different
theories of digestion, tells us that Dr. William Hunter, whose peculiar
sagacity and precision of mind detected at a glance the hollowness of
such delusive hypotheses, and saw the danger which theorists run in
trusting themselves on such slippery ground, expressed himself in his
public lectures, with that solidity of judgment combined with
facetiousness of expression, which rendered him unparalleled as a public
teacher. “Gentlemen,” said he, “Physiologists will have it that the
stomach is a mill—others, that it is a fermenting-vat—others again, that
it is a stew-pan,—but in my view of the matter, it is neither a mill, a
fermenting-vat, nor a stew-pan—but a STOMACH, Gentlemen, a STOMACH.”
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