Pharmacologia: Fourth American, from the Seventh London EditionParis, John Ayrton
Science
Pharmacologia: Fourth American, from the Seventh London Edition
Paris, John Ayrton
Pharmacognosy; Pharmacology; Pharmacy
unequivocal, and it is a question whether in many of such cases the
benefit arising from their use may not depend upon their tonic powers.
As the morbid excess of different evacuations may arise from various and
opposite states of the living system, so may the individuals of the
other classes become astringents; and we are bound to admit upon this,
as we have on other occasions, the existence of _absolute_ and
_relative_ remedies.
Narcotics, at the head of which stands opium, will frequently assume the
character of astringents, by diminishing the irritability upon which
increased discharges depend. In Diarrhœa, an astringent, properly so
called, diminishes the flow of those acrid fluids into the intestines,
by which their peristaltic motions are præternaturally increased, and it
consequently represses the diarrhœa; a narcotic, under similar
circumstances, might not repress the flow of the acrid matter to which I
have alluded, but it would render the bowels less susceptible to its
stimulus, and would therefore produce the same apparent alleviation,
although by a very different mode of operation. There is yet a third
species of remedy, which may operate in restraining a diarrhœa of this
description; not by stopping the flow of acrid matter, nor by
diminishing the irritability of the intestinal organs, as in the
instances above recited, but, simply, by _acting chemically_ upon the
offending matter, so as to disarm it of its acrid qualities; such, for
instance, is the nature of _absorbent_ and _testaceous_ medicines. In
the cure of hemorrhage, if it be _active_, that is to say, connected
with a state of strong tonic contractility of the blood-vessels, a very
different remedy will be required as an astringent, than in cases of
_passive_ hemorrhage, in which the vascular fibres are in a state of
relaxation or collapse. Sir Gilbert Blane has offered some valuable
remarks upon this subject, with a view to settle the difference of
opinion which has arisen respecting the treatment of flooding after
child-birth. (_Medical Logic_, _Edit._ 2d. p. 100.)
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