Pharmacologia: Fourth American, from the Seventh London EditionParis, John Ayrton
Science
Pharmacologia: Fourth American, from the Seventh London Edition
Paris, John Ayrton
Pharmacognosy; Pharmacology; Pharmacy
Although we shall not be disposed to receive this theory in its full
extent, yet we cannot hesitate to admit that the influence of the
nervous system is indispensably necessary for producing vomiting; and we
accordingly find that this act will not take place, however forcibly the
stomach may be goaded by emetics, where the energy of the nervous system
is suspended, as in cases of profound intoxication, or in violent wounds
and contusions of the head; while if the brain be only partially
influenced, as by incipient intoxication, or by a less violent blow upon
the head, its irritability is increased instead of being paralysed, and
vomiting under such circumstances is excited by the slightest causes:
the fact of such opposite results being produced by the same impulse in
different degrees of intensity, is no less curious than instructive. Dr.
Richard Harrison, in his Gulstonian Lecture before the College of
Physicians, treated the subject of vomiting with much ingenuity, and I
am disposed to adopt the views which he offered. He observed, that
although the experiments of Majendie sufficiently testify the importance
of the pressure of the abdominal muscles upon the stomach in the act of
vomiting, and which can only be explained by the influence of the brain
and nervous system, yet that he has attributed too much to their agency;
“it appears to me,” continued he, “that vomiting may be explained in the
following manner:—_the irritation of the stomach makes a call upon the
brain for the aid of the diaphragm and the abdominal muscles, in order
to expel its contents; the diaphragm then becomes contracted and fixed,
the ribs drawn down, and the abdominal muscles drawn inwards, so that
the stomach is pressed on all sides by voluntary muscles, which,
together_ WITH ITS OWN CONTRACTION, _expel the contents_.” Now it must
be obvious that where the brain, from oppression or injury, is unable to
transmit its influence to these muscles,[151] and disregards the call of
the stomach, vomiting can only be excited with difficulty, or it will be
prevented altogether.
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