If the Bella-donna is allowed to be the Στρύχνος μανικὸς of Dioscorides[9], this quality of it was not unknown to that writer. It was very soon known to the first writers in the medical and botanic way after the restoration of letters; and they have not failed to inform us of it. Tragus and Fuchsius, who wrote about the middle of the sixteenth century, both relate instances of the poisonous effects of these berries: the former, of a man, who went mad after having eaten of them; the latter, of two children, who perished by the same means[10]. Lobel[11] tells us, that the berries of this plant are present death; and informs us of some youths, who, after eating them, became stupified, and died as from an over-dose of opium. Matthiolus[12] relates, from his own knowlege, of some children poisoned by the same means. Among all the instances of the intoxicating nature of this plant, there is none more memorable than that mentioned by the Scotch historian Buchanan[13], of the destruction of the army of Sweno; which is quoted by almost all authors, who have wrote upon this plant. It is there said, that the Scots mixed a quantity of the juice of these berries with the drink, which, by their truce, they were to supply the Danes with; which so intoxicated them, that the Scots killed the greatest part of them while they were asleep. How far this anecdote is to be depended upon, or whether other concurrent circumstances ought not to be taken into the account, I cannot determine. Our own herbalist Gerard[14] mentions the case of three boys in the Isle of Ely, who, having eaten of these berries, two of them died in less than eight hours; but the third, by drinking plentifully of honey and water, and vomiting after it, recovered. Bodæus à Stapel, in his comment upon Theophrastus[15], tells us of two youths, that eat two or three of these berries, which they got in the Leyden garden, mistaking them for black currants: one of them perished, and the other recovered with great difficulty. Simon Pauli relates two or three examples to the same effect[16]. Wepfer gives us a circumstantial account of a child about ten years old, who was thrown into a great variety of convulsive symptoms after eating of this fruit: but proper care being taken by vomiting, and afterwards giving alexipharmics and anti-epileptic medicines, he recovered[17]. M. Boulduc[18] laid before the Royal Academy of Sciences at Paris, the case of some children, who, upon eating these berries, were seized with a violent fever, palpitations of the heart, convulsions, and lost their senses. One of them, a little boy of four years old, died the next morning. Boerhaave has instances to the same effect[19]: and it was the misfortune of Dr. Abraham Munting, a noted botanist and professor of physic in the university of Groningen, to have his own daughter poisoned with the berries of the Bella-donna.