From the 1st of April to the 6th the ulcers were firm and dry; but the pain in the breast increased. Several blisters arose on the foot, along the leg, and even upon the thigh, on the left side. One upon the sole of the left foot, for 24 hours discharged an incredible quantity of thick whitish lymph. The pain from these blisters was beyond all she had felt before. It continued the 7th, 8th, and 9th; and new blisters arose on the thigh. The excoriated parts were all dressed with spirit of wine. During the disturbances from these new complaints, the breast was likewise painful, and swelled, tho’ the ulcer near the nipple was dry, and the other discharged little or nothing. The 10th she had less pain both in her foot and in her breast. The upper sore was closed; the foot discharged less. From the 11th to the 15th, notwithstanding the weather was very cold, her pain still lessened. The ulcer remained firm, and the whole breast was softened: her foot mended; and all went on for the better till the 18th, when the ulcer on the upper part of the breast opened again in three places, and discharged a thick yellowish matter. The nipple of the left breast also became inflamed, and surrounded with pimples, which discharged a little lymph. In the mean time the cancerous breast was more painful than on the preceding days. The 19th the pain less, tho’ continual. Some discharge from the foot still; but the ulcers on the thigh were healed, and another blister arose. The 20th the upper sore on the breast closed again; but that near the nipple seemed to threaten another opening, and in fact it did, on the 24th, in three places. On the 20th the catamenia returned very copiously, and superseded the use of the pediluvium. The 25th she began with the infusion of the fourteenth scruple of the Bella-donna, which, it is to be observed, was scarcely ever omitted. The 26th a blister arose at the end of the fore-finger on the left hand, was very painful, and discharged a great quantity of serous matter. The next day both ulcers on the breast discharged a small quantity of lymph; otherwise the breast was less painful. From the 28th of April to the 7th of May every thing went on for the better: the cancerous breast was almost without pain. The ulcers ran very little, but the excoriation and pain were much worse from the nipple of the left breast, which also discharged a great quantity of lymph. The 8th the upper ulcer on the right breast closed; but the other opened again. From the 8th to the 16th no change for the worse: on the contrary, the left breast was well; the right less painful, and discharged but very little. From the 18th to the 22d the menstrual period: all things on the mending hand; the ulcer healed, and the patient had little or no pain: but, from the 23d to the 27th, the pain returned something worse, and there was some discharge from the breast.