laid aside, except the infusion; of which she took a cup-full and an half; but her mouth soon became so dry, that she could scarcely swallow a little tea; and the vertigo was so violent, that she staggered: her sight was so weakened, that she could scarcely read. Notwithstanding this, she had no anxiety, nor nausea, nor pain; but her appetite was less, and her pulse quicker. The 31st all the last-mentioned symptoms continued the same: the two pointed eminences on the upper part of the breast were become two little holes likewise, and had discharged a few drops of good matter. The 1st of February the upper sore had discharged but little matter, and that thinner than before. That near the nipple was become more livid, and the two holes were larger; but there had been no discharge for several days. The pulse and appetite were good, sleep natural, the body open. The pain, indeed, was continual, but less acute. The 2d, little alteration. The sores discharged but little. From this time they were dressed twice in a day with _Nutritum_, and over all the _Emp. Saturnin_. The pain was not so violent, but was felt in another place, which began to swell. From the 6th to the 18th better and worse: the pain more or less acute; and the catamenia passed without any bad effects. At the end of this month the schirrus all over the breast was much softened, and sensibly diminished. This was the opinion of Dr. du Bois and Dr. Winter, as well as of Dr. Lambergen. The 1st of March an inflammation arose on the sole of the right foot, and extended up the leg about four fingers above the heel. It ended in two great blisters, as if from a burn, which were embrocated with wine and oil, and nothing bad followed. To the 22d, the patient was better and worse. The menstrual period did not pass without some disturbance. The 26th she began with the infusion of the tenth scruple, and every thing went on for the better to the end of the month.