I. A widow lady, aged about 50, was seized (December 1755) with a bad cough, oppression about her stomach and breast, and a pain in her right side, tho’ not very acute. Her pulse being quick, and skin hot, some blood was taken away, which was a good deal sizy: attenuating and expectorating medicines were also prescribed. But as her complaints did not yield to these remedies, I was called on December 26th, after she had been ill about ten days; at which time her pulse beat from 96 to 100 times in a minute, but was not fuller than natural. I ordered her to lose seven or eight ounces more of blood, which, like the former, was sizy; and next day, finding no abatement of her complaints, I advised a blister to be applied, in the evening, to that part of her right side which was pained. Next morning, when the blister was removed, the pain of her side was gone, and her pulse beat only 88 times in a minute, and in two days more it came down to 78. However, after the blistered part became dry, the pulse rose in one day’s time to 96, and continued between that number and 90 for four days; after which I ordered a large blister to be put between her shoulders. When this plaister was taken off, her pulse beat under 90 times in a minute; and next day it fell to 76, and the day after to 72. The cough and other symptoms, which were relieved by the first blister, were quite cured by the second. II. John Graham, bookbinder, in Edinburgh, aged 37, of a thin habit of body, formerly subject to coughs, and thought to be in danger of a _phthisis pulmonalis_, having exposed himself unwarily to cold in the night time, was, about the end of January 1756, seized with a bad cough and feverishness; for which he was blooded, and had a diaphoretic julep, a pectoral decoction, and a mixture with _gum. ammoniacum_ and _acetum scilliticum_, given him by Mr. James Russell, surgeon-apothecary in this place. On the 12th of February, after he had been ill above a fortnight, I was desired to visit him. He seemed to be a good deal emaciated; his eyes were hollow, and cheeks fallen in: he was almost constantly in a sweat; coughed frequently, and spit up a great quantity of tough phlegm, somewhat resembling _pus_: his pulse beat from 112 to 116 times in a minute. In this condition I ordered immediately a blister to be applied between his shoulders, which lessened in some degree his cough and spitting, as well as the frequency of his pulse; but the blistered part no sooner began to heal, than he became as ill as before, and continued in this bad way nine or ten days, gradually wasting, with continued sweats, and a great spitting of a thick _mucus_. During this time he used _tinctura rosarum_, and the mixture with _gum. ammon._ and _acet. scillit._ without any sensible benefit, and had six ounces of blood taken away, which was very watery, and the _crassamentum_ was of a lax texture. In this almost desperate condition, another blister, larger than the