I have ascertained by many experiments that the phenomena of galvanism, which are propagated so energetically from the brain towards the organs, which descend, if I may so express myself, along the nerve, will hardly ascend in a contrary direction. Apply the apparatus to a nerve of the loins and the muscles of the upper limbs, and when the communication is made, there will be scarcely any contraction; but on the establishment of a communication between the same nerve and the lower limbs, a violent convulsive motion will instantly be occasioned. I have even observed, on placing two metallic plates, the one under the lumbar nerves, and the other under the upper limbs, that the communication of the two plates by means of a third metal, will cause a contraction of the lower limbs, while the upper limbs remain inactive, or move but feeble.[57] These experiments are particularly applicable to the relation of the heart with the brain; for not only is it true that the section, ligature or compression of the cardiac nerves are of little effect with regard to the functions of the latter, but it is true also, as we shall presently see, that they do not directly modify the movements of the former. We may conclude that the vessels are the exclusive agents of the influence of the heart upon the brain. The vessels, as every one knows, are of two sorts--venous or arterial--they carry black or red blood, the latter answer to the left side, the former to the right side of the heart. Now their functions being very different, the action of one of the portions of this organ on the brain, can never be the same as that of the other portion. We shall inquire in what way they both of them act upon it. In naming these two portions, I shall not make use of the expressions of right and left to distinguish them, but of those of the red-blooded and the black-blooded heart, for each of these portions of itself is an isolated organ, distinct from that to which it is applied, and in the adult especially so. In fact there are two hearts, the one arterial, the other venous, notwithstanding which, we can hardly employ these adjectives for the purpose of designating them, since they both alike possess their arterial and venous appendages. On the other hand, they are neither of them situated exactly to the right or to the left, are neither of them exactly forwards or backwards. Besides which these latter denominations would not apply to animals. I. _In what way does the cessation of the functions of the red-blooded heart interrupt the functions of the brain?_ The red-blooded ventricle and auricle, exert their influence upon the brain by means of the fluid which they send thither through the carotid and vertebral arteries. This fluid may excite the cerebral organ in two ways. 1st. By the movement, with which it is directed. 2nd. By the nature of its colouring principle.