Physiology: The Science of the BodyMartin, Ernest G.
Science
Physiology: The Science of the Body
Martin, Ernest G.
Physiology
pin in anywhere for any distance without striking against one or more of
them. The capillaries are spread so thickly that there are not many
places in the body where living cells are more than a very small
fraction of an inch from one of them. The cells do not, however, lie
right against the capillaries, but are separated from them by tiny
spaces filled with tissue fluid. In order for material to get from the
blood to any living cell, then, it must pass through the wall of the
capillary into the fluid which fills the tissue space and from that in
turn to the cell itself. The wall of the capillaries is so delicate that
if the blood flowing through any capillary contains more of any
substance than is present in the tissue fluid surrounding that
capillary, some of it will pass out through the wall and into the
tissue fluid, just about as freely as though there were no wall there at
all. The arrangement can be illustrated by a familiar example; if a drop
of ink is allowed to fall into a glass of water, it will color only a
small part of the water at first, but quickly spreads out until each
part of the water is as deeply colored as any other part. If the glass
of water were to be divided in half by a very delicate membrane, and the
ink dropped in on one side, it would spread out in the same way, passing
through the membrane in so doing, until again all the water in the glass
was equally colored. Of course, the quickness with which the ink could
pass through the membrane would depend on how delicate the membrane was.
We could imagine membranes which would not let any ink at all through,
and every degree from that up to membranes so delicate as to offer no
obstruction at all to the passage of the ink. The walls of the
capillaries rank as membranes of such delicacy as apparently to offer
almost no obstruction to the passage of materials through them. They
hold back the red corpuscles and the platelets fairly well, so that they
do not pass out of the blood and into the tissue spaces, unless the
capillaries are actually injured. The colorless corpuscles are able to
make their way through the capillary walls and so also do nearly all the
substances that are dissolved in the blood. It is an interesting fact
that the blood proteins do not pass freely through the capillary walls,
although the digestion products of food proteins, do. It will be
remembered that in the chapter on Body Fluids the importance of the
sticky quality of the blood proteins was spoken of. It is now believed
that it is because of this gelatinous nature that the blood proteins
are not able to pass out through the capillary walls, and this is
supposed to be important in the proper working of the circulation. In
fact there is a condition of greatly lowered vitality to which the name
“shock” is applied, in which the blood proteins escape through the
capillary walls to so great an extent as to interfere with the proper
working of the body. It has been found possible to prevent this in a
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