Physiology: The Science of the BodyMartin, Ernest G.
Science
Physiology: The Science of the Body
Martin, Ernest G.
Physiology
Oxyhemoglobin is of a bright scarlet color; hemoglobin itself, not
combined with oxygen, is a very dark purplish color; partial
combinations are brighter and brighter as they contain more oxygen, so
that an expert can judge of the degree to which any specimen of
hemoglobin is combined with oxygen by noting its color in comparison
with fully saturated hemoglobin. The combination of hemoglobin with
oxygen takes place as the blood is passing through the capillaries of
the lungs; therefore the blood which leaves the lungs has the bright
scarlet color characteristic of oxyhemoglobin. This blood is called
arterial blood, the reason is that it is the kind that is found in the
arteries of the body in general. It happens that it makes its first
appearance in the pulmonary vein, by which it is conveyed from the lungs
to the left side of the heart, so that the expression arterial blood
does not mean anything in particular except to describe blood in which
the hemoglobin is saturated with oxygen. This blood is pumped out by the
left side of the heart to all the parts of the body; in its passage
through the capillaries it is in a region where there is active
utilization of oxygen by the living cells. These are steadily taking up
oxygen from the tissue fluids about them, so the blood in the
capillaries, which is carrying an abundant supply of oxygen, is brought
in contact with tissue fluids containing little or none, with only the
delicate wall of the capillaries between. Under these circumstances
rapid diffusion of oxygen from the blood into the tissue fluids takes
place and accompanying this there is a breakdown of oxyhemoglobin, so
that not only most of the oxygen which was dissolved in the blood passes
out, but also a considerable part of that which was formerly in
combination with hemoglobin. Under ordinary circumstances only from
one-fourth to one-third of the oxyhemoglobin decomposes during the rapid
passage of the blood through the capillaries; thus the blood that goes
on into the veins will still be carrying two-thirds or more of the total
oxygen cargo. The color of venous blood will be darker than that of
arterial blood, because it contains a good deal less oxyhemoglobin, but
it is nowhere near so dark as is blood in which all the oxyhemoglobin
has been decomposed. This is well recognized in melodramatic fiction
where the wounds of persons who have met death by strangulation are
described as oozing black blood. It is an actual fact that blood from
which all the oxygen has been withdrawn is so much darker than ordinary
venous blood that it gives the impression of being black, although it is
really a dark purple.
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