Physiology: The Science of the BodyMartin, Ernest G.
Science
Physiology: The Science of the Body
Martin, Ernest G.
Physiology
We spoke a moment ago of hereditary traits whose determiners are bound
up in the sex chromosomes. All such behave interestingly in heredity for
the simple reason that they can never be transmitted from father to son,
but only from father to daughter. This is because, as we have just seen,
the sex chromosome in the sperm always causes the egg which that sperm
fertilizes to develop into a female. The single-sex chromosome which
males possess invariably comes from the mother. An interesting example
is the common type of color blindness known as Daltonism. Normal color
vision is hereditary and the determiners which establish it are in the
sex chromosomes. Occasionally a person is found in whom these
determiners are defective. If this person is a male, he will be color
blind, but if a female not, unless both sex chromosomes are defective in
this regard, since normal color vision is dominant over color blindness;
so if one sex chromosome is normal the vision will be also. The woman,
in this case, will be a hybrid with respect to color vision; one of her
sex chromosomes containing a normal determiner, the other a defective.
This works out in heredity as follows: If a color-blind man is married
to a woman who has no color blindness in her heredity, none of his
children will be color-blind because he cannot transmit the sex
chromosomes which carry the determiners for color blindness to his sons,
but only to his daughters; all the latter will be hybrid with respect to
the character, since all of them come from fertilized eggs which
received sex chromosomes from the sperm. If these daughters, in turn,
marry men who are free from color blindness, some of their sons may be
color-blind, but none of their daughters can be. The only way in which
women can be color blind through inheritance is by descent from
color-blind fathers and from mothers who are either themselves
color-blind or are hybrid with respect to the trait. The result of this
difference in the heredity of the two sexes is to make color blindness
many times as frequent among men as among women. In round numbers four
men out of every hundred have this type of color blindness, while only
six or seven women in ten thousand show it.
Public-domain text, read in full here on John Shaqi.
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