[73] The remarkable influence of mind over matter, and hope over both, was exemplified in 1839, in the person of Surgeon Fraser, of the Bombay establishment. Being reduced almost to a skeleton by a disease, the nature of which could not be ascertained, he happened to see my review of Dr. Granville’s book, and immediately determined to travel _over-land_ to Carlsbad. He embarked in a steamer for Suez—thence was carried in a litter between two camels across the Desert—embarked again at Alexandria for Constantinople—thence through the Black Sea up the Danube, and on to Carlsbad, all this journey being sustained by hope, aided by “change of air.” At Carlsbad the waters were eagerly taken; but alas! were found to do no good! He lost confidence in them, and proceeded to Marienbad in a litter. He died two days after his arrival there, and left his bones in Bohemia! There is little doubt that had he travelled on, instead of stopping at Carlsbad, he might have reached his native mountains in the Highlands. On dissection the disease was found to be in the mesenteric glands. [74] Carlsbad; ses Eaux Minerales. Par De Carro. [75] Sur les Eaux, p. 167. [76] It is a curious fact that the waters of Carlsbad often cause a swelling of the ankles, especially in females. Hoffman was the first who noticed this phenomenon. [77] An English physician has realized a fortune by prescribing on this plan, and enforcing a strict system of diet. The combination used is very nearly the following:— ℞. Infus. rosæ c. ℥viss. Acidi sulph. dil. ʒiss. Magnes sulphat. ℥j. Tinct. gent. c. ℥ss. Sulphatis ferri gr. vij. Misce ft. mistura, capt. coch. ij. mag. primo mane et meridie. I prefer the following formula. ℞. Extr. col. comp. Pil. rhei. comp. aa ℈j. —— hydrargyri gr. vj. Ol. cassiæ, gtt. iv. Misce ft. pil. xij. capt. i. vel. ij. hora somni omni nocte. ℞. Infus. gent. c. ℥vjss. Magnes. sulph. ℥j. Acidi. sulph. aromat. ʒiss. Sulph. ferri. grs. vij. Tinct. aurantii comp. ℥ss. Misce ft. mistura, capt. coch. ij. vel. iij. mag. primo mane, et rept. dosis intra horas duas, si alvus non respondeat. In this formula there is the alterative, the aperient, and the tonic combined, so that no risk is run from any one of the ingredients. In _both_ forms, there is some chemical decomposition, but the physiological effects are good.—J. J. [78] Les Bains de Gastein, p. 34. [79] Erroneously spelled Toeplitz by most travellers.