William Coles, in his ‘Art of Simpling’ (a work published in the year 1656), abandoning for awhile practical instruction, moralises thus:--“Though sin and Sathan have plunged mankinde into an Ocean of Infirmities, yet the mercy of God, which is over all His workes, maketh Grasse to grow upon the Mountaines, and Herbes for the use of men; and hath not only stamped upon them a distinct forme, but also given them particular Signatures, whereby a man may read, even in legible characters, the use of them.” This ancient Doctrine of Signatures was an ingenious system elaborated for discovering from certain marks or appearances on the various portion of a plant’s structure, the supposed medicinal virtue attached to it. A good illustration is to be found in the following passage, translated from P. Lauremberg’s _Apparatus Plantarum_:--“The seed of Garlic is black; it obscures the eyes with blackness and darkness. This is to be understood of healthy eyes, but those which are dull through vicious humidity, from these Garlic drives this viciousness away. The tunic of Garlic is ruddy; it expels blood. It has a hollow stalk, and it helps affections of the wind-pipe.” Many curious details of the system of Plant Signatures are to be found in the works of Porta, Grollius, Schröder, and Kircher: these authorities tell us that there are given, not only in animals, but also in vegetables, certain sure marks, signs, and indications from which their virtues and powers can be inferred by the sagacious and painstaking student. Kircher is of opinion that the Egyptians derived their first knowledge of the elements of medicine from these signs, which they had patiently and closely studied; and in one of his works he enunciates his views in the following passage:--“Since one and all of the members of the human body, under the wise arrangement of Nature, agree or differ with the several objects in the world of creation, by a certain sympathy or antipathy of nature, it follows that there has been implanted by the providence of Nature, both in the several members and in natural objects, a reciprocal instinct, which impels them to seek after those things which are similar and consequently beneficial to themselves, and to avoid and shun those things which are antagonistic or hurtful. Hence has emanated that more recondite part of medicine which compares the Signatures or Characterisms of natural things with the members of the human body, and by magnetically applying like to like produces marvellous effects in the preservation of human health. In this way, the occult properties of plants--first of those that are endowed with life, and secondly of those destitute of life--are indicated by resemblances; for all exhibit to man, by their Signatures and Characterisms, both their powers, by which they can heal, and the diseases in which they are useful. Not only by their parts (as the root, stem, leaf, flower, fruit, and seed), but also by their actions